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FOXC2
Description
forkhead box C2
Image
GO Annotations
Cellular Component
Nuclear Chromatin
Nucleus
Nucleoplasm
Nuclear Body
Molecular Function
RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Chromatin DNA Binding
Identical Protein Binding
Sequence-specific DNA Binding
Transcription Regulatory Region DNA Binding
Promoter-specific Chromatin Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Ossification
Branching Involved In Blood Vessel Morphogenesis
Metanephros Development
Ureteric Bud Development
Somitogenesis
Lymphangiogenesis
Blood Vessel Remodeling
Regulation Of Transcription By RNA Polymerase II
Notch Signaling Pathway
Mesoderm Development
Heart Development
Insulin Receptor Signaling Pathway
Anatomical Structure Morphogenesis
Response To Hormone
Positive Regulation Of Endothelial Cell Migration
Neural Crest Cell Development
Cell Differentiation
Collagen Fibril Organization
Positive Regulation Of Cell Adhesion Mediated By Integrin
Embryonic Heart Tube Development
Positive Regulation Of Vascular Wound Healing
Camera-type Eye Development
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Organ Growth
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Paraxial Mesodermal Cell Fate Commitment
Embryonic Viscerocranium Morphogenesis
Artery Morphogenesis
Ventricular Cardiac Muscle Tissue Morphogenesis
Cardiac Muscle Cell Proliferation
Glomerular Endothelium Development
Glomerular Visceral Epithelial Cell Differentiation
Glomerular Mesangial Cell Development
Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Regulation Of Blood Vessel Diameter
Negative Regulation Of Cold-induced Thermogenesis
Negative Regulation Of Apoptotic Process Involved In Outflow Tract Morphogenesis
Pathways
Drugs
Diseases
Lymphedemas, including: Lymphedema, hereditary I; Lymphedema-distichiasis syndrome (LD); Hypotrichosis-lymphedema-telangiectasia syndrome (HLTS)
GWAS
Metabolite levels (
23823483
)
Nonsyndromic cleft palate (
31609978
)
Nose size (
27182965
)
Sepsis in extremely premature infants (
28283553
)
Systemic juvenile idiopathic arthritis (
27927641
)
Interacting Genes
4 interacting genes:
CNOT7
RBPMS
TAX1BP1
TRIM27
Entrez ID
2303
HPRD ID
03869
Ensembl ID
ENSG00000176692
Uniprot IDs
Q99958
PDB IDs
1D5V
6AKO
6AKP
Enriched GO Terms of Interacting Partners
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