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CEP131

Description centrosomal protein 131
Image No pdb structure
GO Annotations Cellular Component
  • Acrosomal Vesicle
  • Centrosome
  • Cytosol
  • Microtubule Cytoskeleton
  • Centriolar Satellite
  • Ciliary Transition Zone
  • Ciliary Basal Body
  • Intracellular Membrane-bounded Organelle
  • Intercellular Bridge
Molecular Function
  • Protein Binding
  • Protein Homodimerization Activity
  • Protein-containing Complex Binding
Biological Process
  • G2/M Transition Of Mitotic Cell Cycle
  • Multicellular Organism Development
  • Spermatogenesis
  • Positive Regulation Of Cell Proliferation
  • Regulation Of G2/M Transition Of Mitotic Cell Cycle
  • Regulation Of Centrosome Duplication
  • Cell Differentiation
  • Intraciliary Transport Involved In Cilium Assembly
  • Cilium Assembly
  • Protein Localization To Centrosome
  • Positive Regulation Of Intracellular Protein Transport
  • Ciliary Basal Body-plasma Membrane Docking
Pathways
  • Regulation of PLK1 Activity at G2/M Transition
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Anchoring of the basal body to the plasma membrane
  • AURKA Activation by TPX2
Drugs
Diseases
GWAS
  • Frontotemporal dementia ( 26154020)
Interacting Genes 4 interacting genes: MAPKAPK2 MIB1 YWHAE YWHAZ
Entrez ID 22994
HPRD ID 16532
Ensembl ID ENSG00000141577
Uniprot IDs I3L2J8 Q9UPN4
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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