AGTR2

Description		angiotensin II receptor type 2
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GO Annotations	Cellular Component	Cell Plasma Membrane Integral Component Of Plasma Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	G Protein-coupled Receptor Activity Angiotensin Type II Receptor Activity Protein Binding Transcription Factor Binding Receptor Antagonist Activity
	Biological Process	Blood Vessel Remodeling Regulation Of Systemic Arterial Blood Pressure By Circulatory Renin-angiotensin Renin-angiotensin Regulation Of Aldosterone Production Angiotensin-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Brain Renin-angiotensin System Cellular Sodium Ion Homeostasis Inflammatory Response Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Coupled To CGMP Nucleotide Second Messenger Nitric Oxide Mediated Signal Transduction Brain Development Regulation Of Blood Pressure Positive Regulation Of Cell Proliferation Negative Regulation Of Heart Rate Negative Regulation Of Norepinephrine Secretion Cerebellar Cortex Development Negative Regulation Of Cell Growth Negative Regulation Of Icosanoid Secretion Positive Regulation Of Phosphoprotein Phosphatase Activity Intracellular Signal Transduction Regulation Of Metanephros Size Exploration Behavior Positive Regulation Of Renal Sodium Excretion Aldosterone Secretion Angiotensin-activated Signaling Pathway Regulation Of Protein Import Into Nucleus Vasodilation Dopamine Biosynthetic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Fibroblast Proliferation Positive Regulation Of Cytokine Secretion Positive Regulation Of Nitric-oxide Synthase Activity Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Cell Growth Involved In Cardiac Muscle Cell Development Cellular Response To Dexamethasone Stimulus Positive Regulation Of Metanephric Glomerulus Development Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Positive Regulation Of Blood Vessel Diameter Negative Regulation Of Signaling Receptor Activity Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events
Drugs		Tasosartan CYT006-AngQb
Diseases		Non-syndromic X-linked mental retardation
GWAS		Cystic fibrosis severity ( 21602797) Gestational age at birth (maternal effect) ( 28877031) Lung disease severity in cystic fibrosis ( 26417704) Offspring birth weight ( 31043758) Preterm birth (maternal effect) ( 28877031) Type 2 diabetes ( 29358691 30130595)
Interacting Genes		11 interacting genes: ACE AGT AGTRAP ERBB3 ERBIN GNAI2 GNAI3 MTUS1 PIK3CB SNTA1 ZBTB16
Entrez ID		186
HPRD ID		02071
Ensembl ID		ENSG00000180772
Uniprot IDs		P50052
PDB IDs		5UNF 5UNG 5UNH
Enriched GO Terms of Interacting Partners?
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