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DSG2

Description desmoglein 2
Image
GO Annotations Cellular Component
  • Cornified Envelope
  • Plasma Membrane
  • Cell-cell Junction
  • Cell Surface
  • Intercalated Disc
  • Integral Component Of Membrane
  • Apical Plasma Membrane
  • Lateral Plasma Membrane
  • Cell Junction
  • Desmosome
  • Intracellular Membrane-bounded Organelle
  • Extracellular Exosome
Molecular Function
  • Calcium Ion Binding
  • Cell Adhesion Molecule Binding
  • Cell Adhesive Protein Binding Involved In Bundle Of His Cell-Purkinje Myocyte Communication
Biological Process
  • Desmosome Organization
  • Purkinje Myocyte Development
  • Cell Adhesion
  • Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
  • Keratinization
  • Response To Progesterone
  • Maternal Process Involved In Female Pregnancy
  • Cornification
  • Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication
  • Regulation Of Heart Rate By Cardiac Conduction
  • Cell-cell Adhesion
  • Regulation Of Ventricular Cardiac Muscle Cell Action Potential
Pathways
  • Apoptotic cleavage of cell adhesion proteins
  • Keratinization
  • Formation of the cornified envelope
Drugs
Diseases
  • Arrhythmogenic right ventricular cardiomyopathy (ARVC)
GWAS
  • Blood protein levels ( 30072576 29875488)
Interacting Genes 5 interacting genes: DSC1 DSC2 JUP PKP2 PKP3
Entrez ID 1829
HPRD ID 00516
Ensembl ID ENSG00000046604
Uniprot IDs Q14126
PDB IDs 2YQG 5ERD 5J5J 6QNT 6QNU
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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