Wiki-CORONA
  • About
  • Search
  • Browse
  • Data Sources
  • People
  • Funding
  • Advanced Search

CYP51A1

Description cytochrome P450 family 51 subfamily A member 1
Image
GO Annotations Cellular Component
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Plasma Membrane
  • Membrane
  • Integral Component Of Membrane
Molecular Function
  • Iron Ion Binding
  • Sterol 14-demethylase Activity
  • Oxidoreductase Activity
  • Heme Binding
Biological Process
  • Steroid Biosynthetic Process
  • Cholesterol Biosynthetic Process
  • Sterol Metabolic Process
  • Sterol Biosynthetic Process
  • Cholesterol Biosynthetic Process Via 24,25-dihydrolanosterol
  • Negative Regulation Of Protein Catabolic Process
  • Regulation Of Cholesterol Biosynthetic Process
  • Negative Regulation Of Protein Secretion
  • Oxidation-reduction Process
  • Demethylation
  • Negative Regulation Of Amyloid-beta Clearance
Pathways
  • Cholesterol biosynthesis
  • Endogenous sterols
  • Activation of gene expression by SREBF (SREBP)
  • EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
  • Metronidazole
  • Tioconazole
  • Rifampicin
  • Itraconazole
  • 1-[(2S)-2-[(4-CHLOROBENZYL)OXY]-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE
Diseases
GWAS
  • Hippocampal volume in Alzheimer's disease dementia ( 29274321)
  • Lifespan ( 25918517)
  • Pulse pressure ( 30578418)
Interacting Genes 1 interacting genes: ZNF420
Entrez ID 1595
HPRD ID 03381
Ensembl ID ENSG00000001630
Uniprot IDs A0A0C4DFL7 Q16850
PDB IDs 3JUS 3JUV 3LD6 4UHI 4UHL 6Q2T
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

  • Tweet