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SIK1

Description salt inducible kinase 1
Image No pdb structure
GO Annotations Cellular Component
  • Nucleus
  • Cytoplasm
Molecular Function
  • Magnesium Ion Binding
  • Protein Serine/threonine Kinase Activity
  • Protein Binding
  • ATP Binding
  • CAMP Response Element Binding Protein Binding
  • Protein Kinase Binding
  • 14-3-3 Protein Binding
Biological Process
  • Regulation Of Sodium Ion Transport
  • Protein Phosphorylation
  • Cell Cycle
  • Regulation Of Mitotic Cell Cycle
  • Regulation Of Myotube Differentiation
  • Negative Regulation Of Triglyceride Biosynthetic Process
  • Negative Regulation Of CREB Transcription Factor Activity
  • Intracellular Signal Transduction
  • Entrainment Of Circadian Clock By Photoperiod
  • Regulation Of Cell Differentiation
  • Negative Regulation Of Gluconeogenesis
  • Protein Autophosphorylation
  • Rhythmic Process
  • Cardiac Muscle Cell Differentiation
  • Positive Regulation Of Anoikis
Pathways
  • Circadian Clock
Drugs
  • Dabrafenib
Diseases
GWAS
  • Allergic disease (asthma, hay fever or eczema) ( 29083406)
  • Alzheimer disease and age of onset ( 26830138)
  • Blond vs. brown/black hair color ( 30531825)
  • Diastolic blood pressure ( 28135244 27841878 28739976 27618452)
  • Red vs. brown/black hair color ( 30531825)
  • Systolic blood pressure ( 27841878 28739976 27618452)
Interacting Genes 13 interacting genes: CRTC2 GINS4 HDAC5 MAPT MCM2 NMNAT1 PRKACA RNF2 RPL3 STK11 SUPT5H VAPA YWHAZ
Entrez ID 150094
HPRD ID 09301
Ensembl ID ENSG00000142178
Uniprot IDs P57059
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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