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RAD9B

Description RAD9 checkpoint clamp component B
Image No pdb structure
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Checkpoint Clamp Complex
Molecular Function
  • Protein Binding
  • 3'-5' Exonuclease Activity
Biological Process
  • DNA Replication Checkpoint
  • DNA Replication
  • DNA Repair
  • Intra-S DNA Damage Checkpoint
  • Cellular Response To Ionizing Radiation
  • Nucleic Acid Phosphodiester Bond Hydrolysis
  • Regulation Of Signal Transduction By P53 Class Mediator
Pathways
  • Activation of ATR in response to replication stress
  • HDR through Single Strand Annealing (SSA)
  • Processing of DNA double-strand break ends
  • Presynaptic phase of homologous DNA pairing and strand exchange
  • Regulation of TP53 Activity through Phosphorylation
  • G2/M DNA damage checkpoint
Drugs
Diseases
GWAS
Interacting Genes 5 interacting genes: HUS1 HUS1B RAD1 RAD17 RAD9A
Entrez ID 144715
HPRD ID 12221
Ensembl ID ENSG00000151164
Uniprot IDs A0A024RBJ5 A0A024RBN9 B4DX60 B4DYM6 J3KPN7 Q6WBX8
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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