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COL8A2

Description collagen type VIII alpha 2 chain
Image No pdb structure
GO Annotations Cellular Component
  • Extracellular Region
  • Collagen Trimer
  • Basement Membrane
  • Extracellular Space
  • Endoplasmic Reticulum Lumen
  • Extracellular Matrix
  • Collagen-containing Extracellular Matrix
Molecular Function
  • Extracellular Matrix Structural Constituent
  • Extracellular Matrix Structural Constituent Conferring Tensile Strength
  • Protein Binding, Bridging
Biological Process
  • Angiogenesis
  • Extracellular Matrix Organization
  • Camera-type Eye Morphogenesis
  • Epithelial Cell Proliferation
  • Cell-cell Adhesion
Pathways
  • Collagen degradation
  • Collagen degradation
  • Collagen biosynthesis and modifying enzymes
  • Assembly of collagen fibrils and other multimeric structures
  • Integrin cell surface interactions
  • Collagen chain trimerization
Drugs
Diseases
  • Posterior polymorphous corneal dystrophy (PPCD)
  • Fuchs corneal dystrophy (FECD); Fuchs endothelial corneal dystrophy
GWAS
  • Central corneal thickness ( 29760442)
  • Corneal structure ( 23291589)
  • Early spontaneous preterm birth ( 31194736)
  • Intraocular pressure ( 29617998 29785010 31959993)
Interacting Genes 3 interacting genes: COL8A1 LMNA SGTA
Entrez ID 1296
HPRD ID 08347
Ensembl ID ENSG00000171812
Uniprot IDs E9PP49 P25067
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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