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CMA1

Description chymase 1
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Extracellular Space
  • Cell
  • Cytoplasm
  • Secretory Granule
  • Collagen-containing Extracellular Matrix
Molecular Function
  • Serine-type Endopeptidase Activity
  • Serine-type Peptidase Activity
  • Peptide Binding
Biological Process
  • Angiotensin Maturation
  • Extracellular Matrix Disassembly
  • Midbrain Development
  • Basement Membrane Disassembly
  • Positive Regulation Of Angiogenesis
  • Interleukin-1 Beta Biosynthetic Process
  • Regulation Of Inflammatory Response
  • Cellular Response To Glucose Stimulus
Pathways
  • Signaling by SCF-KIT
  • Activation of Matrix Metalloproteinases
  • Metabolism of Angiotensinogen to Angiotensins
Drugs
  • Benzylsulfinic Acid
  • 2-(N-Morpholino)-Ethanesulfonic Acid
  • 2-[3-({Methyl[1-(2-Naphthoyl)Piperidin-4-Yl]Amino}Carbonyl)-2-Naphthyl]-1-(1-Naphthyl)-2-Oxoethylphosphonic Acid
  • [(1S)-1-(5-CHLORO-1-BENZOTHIEN-3-YL)-2-(2-NAPHTHYLAMINO)-2-OXOETHYL]PHOSPHONIC ACID
Diseases
GWAS
Interacting Genes 10 interacting genes: AGT EDN1 EDN2 EDN3 FYN IL1B KITLG MMP1 PFN1 SERPINA3
Entrez ID 1215
HPRD ID 00346
Ensembl ID ENSG00000092009
Uniprot IDs P23946 Q4FEB3
PDB IDs 1KLT 1NN6 1PJP 1T31 2HVX 3N7O 3S0N 4AFQ 4AFS 4AFU 4AFZ 4AG1 4AG2 4K2Y 4K5Z 4K60 4K69 4KP0 5YJM 5YJP
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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