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NEDD1

Description NEDD1 gamma-tubulin ring complex targeting factor
Image No pdb structure
GO Annotations Cellular Component
  • Pericentriolar Material
  • Spindle Pole
  • Nucleoplasm
  • Centrosome
  • Centriole
  • Cytosol
  • Plasma Membrane
  • Ciliary Basal Body
  • Apical Part Of Cell
Molecular Function
  • Protein Binding
Biological Process
  • G2/M Transition Of Mitotic Cell Cycle
  • Regulation Of G2/M Transition Of Mitotic Cell Cycle
  • Cell Division
  • Protein Localization To Centrosome
  • Ciliary Basal Body-plasma Membrane Docking
Pathways
  • Regulation of PLK1 Activity at G2/M Transition
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Anchoring of the basal body to the plasma membrane
  • AURKA Activation by TPX2
Drugs
Diseases
GWAS
  • Adventurousness ( 30643258)
  • Autism ( 24189344)
  • Breast size ( 22747683)
  • Frontotemporal dementia ( 29724592)
  • Frontotemporal dementia with GRN mutation ( 29724592)
  • Manganese levels ( 26025379)
Interacting Genes 2 interacting genes: EP300 FBLN1
Entrez ID 121441
HPRD ID 02655
Ensembl ID ENSG00000139350
Uniprot IDs A0A024RBE5 A8K1Z3 Q8NHV4
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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