SP7

Description		Sp7 transcription factor
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DEAD/H-box RNA Helicase Binding Metal Ion Binding
	Biological Process	Osteoblast Differentiation Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Hematopoietic Stem Cell Differentiation Positive Regulation Of Stem Cell Differentiation
Pathways		RUNX2 regulates osteoblast differentiation
Drugs
Diseases
GWAS		Bone mineral density (spine) ( 19079262 19801982) Heel bone mineral density ( 30598549) Height ( 31562340) Hypospadias (moderate to severe) ( 31856834) Lumbar spine bone mineral density ( 22504420) Mean corpuscular hemoglobin ( 29403010)
Interacting Genes		2 interacting genes: CBL CBLB
Entrez ID		121340
HPRD ID		05971
Ensembl ID		ENSG00000170374
Uniprot IDs		A0A024RAY8 Q8TDD2
PDB IDs
Enriched GO Terms of Interacting Partners?
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