ADCY1

Description		adenylate cyclase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Membrane Raft Extracellular Exosome Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse Integral Component Of Postsynaptic Density Membrane
	Molecular Function	Adenylate Cyclase Activity Calmodulin Binding ATP Binding Calcium- And Calmodulin-responsive Adenylate Cyclase Activity Metal Ion Binding
	Biological Process	Renal Water Homeostasis CAMP Biosynthetic Process G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Axonogenesis Brain Development Long-term Memory Circadian Rhythm Response To Lithium Ion CAMP-mediated Signaling Positive Regulation Of CREB Transcription Factor Activity Activation Of Protein Kinase A Activity Regulation Of Circadian Rhythm Cellular Response To Calcium Ion Cellular Response To Glucagon Stimulus Neuroinflammatory Response Positive Regulation Of Long-term Synaptic Potentiation Cellular Response To Forskolin Regulation Of Synaptic Vesicle Exocytosis
Pathways		Glucagon signaling in metabolic regulation PKA activation PKA activation in glucagon signalling Adenylate cyclase activating pathway Adenylate cyclase inhibitory pathway Adenylate cyclase inhibitory pathway G alpha (s) signalling events G alpha (s) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events Vasopressin regulates renal water homeostasis via Aquaporins CREB1 phosphorylation through the activation of Adenylate Cyclase Hedgehog 'off' state ADORA2B mediated anti-inflammatory cytokines production ADORA2B mediated anti-inflammatory cytokines production FCGR3A-mediated IL10 synthesis
Drugs		Adenosine monophosphate ATP
Diseases
GWAS		Bipolar disorder lithium response (continuous) or schizophrenia ( 29121268) Night sleep phenotypes ( 27126917) Subjective response to lithium treatment in bipolar disorder ( 26503763)
Interacting Genes		3 interacting genes: ADCY2 GNAI2 SERTAD1
Entrez ID		107
HPRD ID		00053
Ensembl ID		ENSG00000164742
Uniprot IDs		C9J1J0 Q08828
PDB IDs
Enriched GO Terms of Interacting Partners?
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