Search Results for: TUBB4A

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
Novel ABCA7 ATP binding cassette subfamily A member 7
  • ABC transporters in lipid homeostasis
Novel APC2 APC regulator of WNT signaling pathway 2
  • Colorectal cancer
Novel HMG20B high mobility group 20B
  • HDACs deacetylate histones
  • Potential therapeutics for SARS
  • Factors involved in megakaryocyte development and platelet production
Novel KDM4B lysine demethylase 4B
  • HDMs demethylate histones
  • Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
  • Estrogen-dependent gene expression
Novel PLIN3 perilipin 3
  • Triglyceride catabolism
  • Retrograde transport at the Trans-Golgi-Network
  • Lipophagy
  • Chaperone Mediated Autophagy
  • Late endosomal microautophagy
  • RHOBTB3 ATPase cycle
  • Idursulfase
  • Galsulfase
Novel SBNO2 strawberry notch homolog 2
Novel UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI
  • Respiratory electron transport
  • 6-Hydroxy-5-undecyl-4,7-benzothiazoledione
  • Azoxystrobin
  • (S)-famoxadone
  • 2-Nonyl-4-quinolinol 1-oxide
  • Ubiquinone Q2
BMPR2 bone morphogenetic protein receptor type 2
  • Signaling by BMP
  • Dibotermin alfa
  • Fostamatinib
CLN8 CLN8 transmembrane ER and ERGIC protein
  • Neuronal ceroid lipofuscinosis, including: Infantile Neuronal Ceroid Lipofuscinosis (INCL)/ Santavuori-Haltia Disease (CLN1); Late-Infantile Neuronal Ceroid Lipofuscinosis (LINCL)/ Jansky-Bielschowsky Disease (CLN2); Juvenile Neuronal Ceroid Lipofuscinosis (JNCL)/Batten Disease/ Spielmeyer-Vogt Disease (CLN3); Adult Neuronal Ceroid Lipofuscinosis (ANCL)/ Kufs Disease (CLN4); LINCL variant (CLN5, CLN6, CLN7, CLN8); Batten Disease variant (CLN9); Congenital NCL (CLN10)
  • Progressive myoclonic epilepsy (PME), including: Lafora disease (LBD); Unverricht-Lundborg disease (ULD); Neuronal ceroid lipofuscinoses (NCL); Type I sialidosis; Action myoclonus-renal failure syndrome (AMRF); Type III Gaucher disease (GD)
LINC01554 long intergenic non-protein coding RNA 1554
NEAT1 nuclear paraspeckle assembly transcript 1
NR4A1 nuclear receptor subfamily 4 group A member 1
  • AKT phosphorylates targets in the nucleus
  • Nuclear Receptor transcription pathway
  • Constitutive Signaling by AKT1 E17K in Cancer
SELENOF selenoprotein F
STAU1 staufen double-stranded RNA binding protein 1
STK11 serine/threonine kinase 11
  • AMPK inhibits chREBP transcriptional activation activity
  • Energy dependent regulation of mTOR by LKB1-AMPK
  • Regulation of TP53 Activity through Phosphorylation
  • FOXO-mediated transcription of cell death genes
  • Peutz-Jeghers syndrome
  • Pancreatic cancer
SUMO2 small ubiquitin like modifier 2
  • Vitamin D (calciferol) metabolism
  • SUMO is conjugated to E1 (UBA2:SAE1)
  • SUMO is transferred from E1 to E2 (UBE2I, UBC9)
  • SUMO is proteolytically processed
  • SUMOylation of DNA damage response and repair proteins
  • SUMOylation of transcription factors
  • SUMOylation of transcription cofactors
  • SUMOylation of SUMOylation proteins
  • SUMOylation of intracellular receptors
  • SUMOylation of intracellular receptors
  • SUMOylation of chromatin organization proteins
  • SUMOylation of RNA binding proteins
  • SUMOylation of DNA replication proteins
  • Processing of DNA double-strand break ends
  • Formation of Incision Complex in GG-NER
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
  • Activation of BAD and translocation to mitochondria
  • Translocation of SLC2A4 (GLUT4) to the plasma membrane
  • Regulation of PLK1 Activity at G2/M Transition
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Anchoring of the basal body to the plasma membrane
  • RHO GTPases activate PKNs
  • TP53 Regulates Metabolic Genes
  • Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
  • AURKA Activation by TPX2
  • Regulation of localization of FOXO transcription factors

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