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LAPTM4A |
lysosomal protein transmembrane 4 alpha |
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LIG1 |
DNA ligase 1 |
- POLB-Dependent Long Patch Base Excision Repair
- Early Phase of HIV Life Cycle
- Processive synthesis on the C-strand of the telomere
- Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
- Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
- PCNA-Dependent Long Patch Base Excision Repair
- Gap-filling DNA repair synthesis and ligation in GG-NER
- Gap-filling DNA repair synthesis and ligation in TC-NER
- Processive synthesis on the lagging strand
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- DNA repair defects, including the following six diseases: Ataxia telangiectasia (AT); Ataxia-talangiectasia-like syndrome; Nijmegen syndrome; DNA ligase I deficiency; DNA ligase IV deficiency; Bloom's syndrome
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LINC01554 |
long intergenic non-protein coding RNA 1554 |
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MAP7D3 |
MAP7 domain containing 3 |
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MAPT |
microtubule associated protein tau |
- Caspase-mediated cleavage of cytoskeletal proteins
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- Lansoprazole
- Astemizole
- Paclitaxel
- Docetaxel
- Flortaucipir F-18
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- Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
- Frontotemporal lobar degeneration (FTLD), including: Pick disease of brain; Frontotemporal dementia (FTD); Ubiquitin-positive frontotemporal dementia (UP-FTD); Progressive supranuclear palsy type 1 (PSNP1); Inclusion body myopathy with early-onset paget disease and frontotemporal dementia (IBMPFD); Frontotemporal dementia, chromosome 3-linked (FTD3)
- Progressive supranuclear palsy (PSP); Steele-Richardson-Olszewski syndrome
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MRPL28 |
mitochondrial ribosomal protein L28 |
- Mitochondrial translation initiation
- Mitochondrial translation elongation
- Mitochondrial translation elongation
- Mitochondrial translation termination
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MTCL1 |
microtubule crosslinking factor 1 |
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MTDH |
metadherin |
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PHIP |
pleckstrin homology domain interacting protein |
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PLK1 |
polo like kinase 1 |
- Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
- Polo-like kinase mediated events
- Golgi Cisternae Pericentriolar Stack Reorganization
- Golgi Cisternae Pericentriolar Stack Reorganization
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Phosphorylation of the APC/C
- Phosphorylation of Emi1
- Condensation of Prophase Chromosomes
- Separation of Sister Chromatids
- Resolution of Sister Chromatid Cohesion
- Regulation of PLK1 Activity at G2/M Transition
- Activation of NIMA Kinases NEK9, NEK6, NEK7
- Loss of Nlp from mitotic centrosomes
- Recruitment of mitotic centrosome proteins and complexes
- Loss of proteins required for interphase microtubule organization from the centrosome
- Recruitment of NuMA to mitotic centrosomes
- Anchoring of the basal body to the plasma membrane
- RHO GTPases Activate Formins
- Mitotic Prometaphase
- Mitotic Metaphase/Anaphase Transition
- Mitotic Telophase/Cytokinesis
- Cyclin A/B1/B2 associated events during G2/M transition
- The role of GTSE1 in G2/M progression after G2 checkpoint
- AURKA Activation by TPX2
- EML4 and NUDC in mitotic spindle formation
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- 3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}isoxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol
- 3-[3-(3-methyl-6-{[(1S)-1-phenylethyl]amino}-1H-pyrazolo[4,3-c]pyridin-1-yl)phenyl]propanamide
- 4-(4-METHYLPIPERAZIN-1-YL)-N-[5-(2-THIENYLACETYL)-1,5-DIHYDROPYRROLO[3,4-C]PYRAZOL-3-YL]BENZAMIDE
- 1-[5-Methyl-2-(trifluoromethyl)furan-3-yl]-3-[5-[2-[[6-(1H-1,2,4-triazol-5-ylamino)pyrimidin-4-yl]amino]ethyl]-1,3-thiazol-2-yl]urea
- Wortmannin
- Fostamatinib
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RCC1 |
regulator of chromosome condensation 1 |
- Rev-mediated nuclear export of HIV RNA
- Nuclear import of Rev protein
- Postmitotic nuclear pore complex (NPC) reformation
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RILPL2 |
Rab interacting lysosomal protein like 2 |
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ROBO1 |
roundabout guidance receptor 1 |
- Netrin-1 signaling
- Signaling by ROBO receptors
- Signaling by ROBO receptors
- Activation of RAC1
- Regulation of commissural axon pathfinding by SLIT and ROBO
- Regulation of commissural axon pathfinding by SLIT and ROBO
- Inactivation of CDC42 and RAC1
- Role of ABL in ROBO-SLIT signaling
- Role of ABL in ROBO-SLIT signaling
- SLIT2:ROBO1 increases RHOA activity
- Regulation of cortical dendrite branching
- Regulation of expression of SLITs and ROBOs
- Regulation of expression of SLITs and ROBOs
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SEL1L3 |
SEL1L family member 3 |
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SMN1 |
survival of motor neuron 1, telomeric |
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- Spinal muscular atrophy (SMA), including: SMA type I (SMA1) / Werdning-Hoffman disease; SMA type II (SMA2); SMA type III (SMA3) / Kugeleberg-Welander disease; SMA type IV (SMA4); X-linked SMA 2 (SMAX2); X-linked distal SMA 3 (DSMAX); Distal SMA autosomal recessive type 4 (DSMA4); Congenital distal spinal muscular atrophy (SMAL); SMA proximal adult autosomal dominant (SMAPAD)
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SPTSSA |
serine palmitoyltransferase small subunit A |
- Sphingolipid de novo biosynthesis
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TERF1 |
telomeric repeat binding factor 1 |
- Recognition and association of DNA glycosylase with site containing an affected pyrimidine
- Cleavage of the damaged pyrimidine
- Recognition and association of DNA glycosylase with site containing an affected purine
- Recognition and association of DNA glycosylase with site containing an affected purine
- Cleavage of the damaged purine
- Cleavage of the damaged purine
- Meiotic synapsis
- Packaging Of Telomere Ends
- Telomere Extension By Telomerase
- Polymerase switching on the C-strand of the telomere
- Processive synthesis on the C-strand of the telomere
- Telomere C-strand (Lagging Strand) Synthesis
- Telomere C-strand synthesis initiation
- Removal of the Flap Intermediate from the C-strand
- DNA Damage/Telomere Stress Induced Senescence
- Inhibition of DNA recombination at telomere
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TF |
transferrin |
- Platelet degranulation
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- Cargo recognition for clathrin-mediated endocytosis
- Clathrin-mediated endocytosis
- Post-translational protein phosphorylation
- Iron uptake and transport
- Transferrin endocytosis and recycling
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- Cisplatin
- Isoflurophate
- Aluminium
- Iron
- Zinc
- Manganese
- Copper
- Dichlorvos
- Zinc acetate
- Ferrous gluconate
- Ferrous succinate
- Ferrous ascorbate
- Ferrous fumarate
- Ferrous glycine sulfate
- Aluminium phosphate
- Aluminum acetate
- Zinc chloride
- Zinc sulfate, unspecified form
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TK1 |
thymidine kinase 1 |
- G1/S-Specific Transcription
- Pyrimidine salvage
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- Dithioerythritol
- Thymidine 5'-triphosphate
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TPTE |
transmembrane phosphatase with tensin homology |
- Synthesis of PIPs at the Golgi membrane
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