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DDX20 |
DEAD-box helicase 20 |
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DDX5 |
DEAD-box helicase 5 |
- SUMOylation of transcription cofactors
- mRNA Splicing - Major Pathway
- Estrogen-dependent gene expression
- Replication of the SARS-CoV-1 genome
- Replication of the SARS-CoV-2 genome
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DGKZ |
diacylglycerol kinase zeta |
- Effects of PIP2 hydrolysis
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- alpha-Tocopherol succinate
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DHCR24 |
24-dehydrocholesterol reductase |
- Cholesterol biosynthesis via desmosterol
- Cholesterol biosynthesis via lathosterol
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DHFR |
dihydrofolate reductase |
- Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
- Metabolism of folate and pterines
- G1/S-Specific Transcription
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- NADH
- Pyrimethamine
- Methotrexate
- Pemetrexed
- Gentamicin
- Proguanil
- Trimetrexate
- 2,4-Diamino-5-Methyl-6-[(3,4,5-Trimethoxy-N-Methylanilino)Methyl]Pyrido[2,3-D]Pyrimidine
- 2,4-Diamino-6-[N-(2',5'-Dimethoxybenzyl)-N-Methylamino]Quinazoline
- 6-(Octahydro-1h-Indol-1-Ylmethyl)Decahydroquinazoline-2,4-Diamine
- N6-(2,5-Dimethoxy-Benzyl)-N6-Methyl-Pyrido[2,3-D]Pyrimidine-2,4,6-Triamine
- 2,4-Diamino-6-[N-(3',4',5'-Trimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine
- Sri-9662
- 2,4-Diamino-5-(3,4,5-Trimethoxy-Benzyl)-Pyrimidin-1-Ium
- Sri-9439
- Nicotinamide adenine dinucleotide phosphate
- Piritrexim
- Biopterin
- 2,4-Diamino-6-[N-(3',5'-Dimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine
- Iclaprim
- Pralatrexate
- 5-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
- 5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
- 5-[(3R)-3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
- 5-[(3R)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
- 5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine
- [N-(2,4-DIAMINOPTERIDIN-6-YL)-METHYL]-DIBENZ[B,F]AZEPINE
- (4aS)-5-[(2,4-diaminopteridin-6-yl)methyl]-4a,5-dihydro-2H-dibenzo[b,f]azepin-8-ol
- (2R,6S)-6-{[methyl(3,4,5-trimethoxyphenyl)amino]methyl}-1,2,5,6,7,8-hexahydroquinazoline-2,4-diamine
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DLEU1 |
deleted in lymphocytic leukemia 1 |
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DMTF1 |
cyclin D binding myb like transcription factor 1 |
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DNAJB1 |
DnaJ heat shock protein family (Hsp40) member B1 |
- Regulation of HSF1-mediated heat shock response
- HSP90 chaperone cycle for steroid hormone receptors (SHR)
- Attenuation phase
- HSF1-dependent transactivation
- MAPK6/MAPK4 signaling
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DNAJC7 |
DnaJ heat shock protein family (Hsp40) member C7 |
- Regulation of HSF1-mediated heat shock response
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DNMT3L |
DNA methyltransferase 3 like |
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DTL |
denticleless E3 ubiquitin protein ligase homolog |
- Recognition of DNA damage by PCNA-containing replication complex
- Neddylation
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DVL2 |
dishevelled segment polarity protein 2 |
- TCF dependent signaling in response to WNT
- WNT mediated activation of DVL
- Signaling by Hippo
- PCP/CE pathway
- PCP/CE pathway
- Asymmetric localization of PCP proteins
- Degradation of DVL
- Disassembly of the destruction complex and recruitment of AXIN to the membrane
- Disassembly of the destruction complex and recruitment of AXIN to the membrane
- WNT5A-dependent internalization of FZD4
- Negative regulation of TCF-dependent signaling by DVL-interacting proteins
- RHO GTPases Activate Formins
- Cargo recognition for clathrin-mediated endocytosis
- Clathrin-mediated endocytosis
- WNT5:FZD7-mediated leishmania damping
- WNT5:FZD7-mediated leishmania damping
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E2F1 |
E2F transcription factor 1 |
- Activation of NOXA and translocation to mitochondria
- Inhibition of replication initiation of damaged DNA by RB1/E2F1
- Transcription of E2F targets under negative control by DREAM complex
- Transcription of E2F targets under negative control by DREAM complex
- Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
- Activation of PUMA and translocation to mitochondria
- Pre-NOTCH Transcription and Translation
- Pre-NOTCH Transcription and Translation
- Oxidative Stress Induced Senescence
- Oncogene Induced Senescence
- TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
- CDC6 association with the ORC:origin complex
- G2 Phase
- Cyclin E associated events during G1/S transition
- G1/S-Specific Transcription
- G1/S-Specific Transcription
- Cyclin D associated events in G1
- Cyclin A:Cdk2-associated events at S phase entry
- Transcriptional Regulation by E2F6
- Transcriptional regulation of granulopoiesis
- Transcriptional regulation of granulopoiesis
- Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
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E4F1 |
E4F transcription factor 1 |
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EAF2 |
ELL associated factor 2 |
- Formation of RNA Pol II elongation complex
- RNA Polymerase II Pre-transcription Events
- RNA Polymerase II Transcription Elongation
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EEF2 |
eukaryotic translation elongation factor 2 |
- Peptide chain elongation
- Peptide chain elongation
- Uptake and function of diphtheria toxin
- Synthesis of diphthamide-EEF2
- Synthesis of diphthamide-EEF2
- Neutrophil degranulation
- Protein methylation
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- Adenosine-5-Diphosphoribose
- Diphthamide
- Guanosine-5'-Diphosphate
- N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE
- Esketamine
- Moxetumomab Pasudotox
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EFEMP2 |
EGF containing fibulin extracellular matrix protein 2 |
- Molecules associated with elastic fibres
- Molecules associated with elastic fibres
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- Cutis laxa, including: Autosomal dominant cutis laxa (ADCL); Autosomal recessive cutis laxa I (ARCL1); Autosomal recessive cutis laxa II (ARCL2); X-linked recessive cutis laxa (XRCL); Wrinkly skin syndrome
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EGLN3 |
egl-9 family hypoxia inducible factor 3 |
- Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
- Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
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EGR1 |
early growth response 1 |
- Regulation of PTEN gene transcription
- Regulation of PTEN gene transcription
- NGF-stimulated transcription
- NGF-stimulated transcription
- Interferon alpha/beta signaling
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EHMT1 |
euchromatic histone lysine methyltransferase 1 |
- Senescence-Associated Secretory Phenotype (SASP)
- PKMTs methylate histone lysines
- Regulation of TP53 Activity through Methylation
- Transcriptional Regulation by VENTX
- Transcriptional Regulation by E2F6
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- Kleefstra syndrome; 9q Subtelomeric deletion syndrome
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