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MED12 |
mediator complex subunit 12 |
- PPARA activates gene expression
- Generic Transcription Pathway
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
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- FG syndrome (FGS); Opitz-Kaveggia syndrome
- MED12-related disorders, including: Lujan-Fryns syndrome (LFS); Lujan syndrome; X-linked mental retardation with Marfanoid habitus; FG syndrome type 1 (FGS1); Opitz-Kaveggia syndrome
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MED13 |
mediator complex subunit 13 |
- PPARA activates gene expression
- Generic Transcription Pathway
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
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MED14 |
mediator complex subunit 14 |
- PPARA activates gene expression
- Generic Transcription Pathway
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
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MED16 |
mediator complex subunit 16 |
- PPARA activates gene expression
- Generic Transcription Pathway
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
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MED17 |
mediator complex subunit 17 |
- PPARA activates gene expression
- Generic Transcription Pathway
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
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MED20 |
mediator complex subunit 20 |
- PPARA activates gene expression
- Generic Transcription Pathway
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
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MED21 |
mediator complex subunit 21 |
- PPARA activates gene expression
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
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MED23 |
mediator complex subunit 23 |
- PPARA activates gene expression
- Generic Transcription Pathway
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
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MED24 |
mediator complex subunit 24 |
- PPARA activates gene expression
- Generic Transcription Pathway
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
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MED27 |
mediator complex subunit 27 |
- PPARA activates gene expression
- Generic Transcription Pathway
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
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MED6 |
mediator complex subunit 6 |
- PPARA activates gene expression
- Generic Transcription Pathway
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
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MED7 |
mediator complex subunit 7 |
- PPARA activates gene expression
- Generic Transcription Pathway
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
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MEN1 |
menin 1 |
- Formation of the beta-catenin:TCF transactivating complex
- SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
- Deactivation of the beta-catenin transactivating complex
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- RHO GTPases activate IQGAPs
- Post-translational protein phosphorylation
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- Carcinoid
- Adrenal carcinoma
- Primary hyperparathyroidism; Familial hyperparathyroidism (HRPT)
- Malignant islet cell carcinoma
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MGMT |
O-6-methylguanine-DNA methyltransferase |
- MGMT-mediated DNA damage reversal
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- Cysteine
- Zinc
- S-Methylcysteine
- S-Benzylcysteine
- Dinitrochlorobenzene
- Zinc acetate
- Zinc chloride
- Zinc sulfate, unspecified form
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MKNK2 |
MAPK interacting serine/threonine kinase 2 |
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MMS19 |
MMS19 homolog, cytosolic iron-sulfur assembly component |
- Cytosolic iron-sulfur cluster assembly
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MNAT1 |
MNAT1 component of CDK activating kinase |
- Formation of RNA Pol II elongation complex
- Formation of the Early Elongation Complex
- Formation of HIV elongation complex in the absence of HIV Tat
- Formation of the HIV-1 Early Elongation Complex
- RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
- HIV Transcription Initiation
- RNA Polymerase II HIV Promoter Escape
- Transcription of the HIV genome
- Formation of HIV-1 elongation complex containing HIV-1 Tat
- Tat-mediated elongation of the HIV-1 transcript
- NoRC negatively regulates rRNA expression
- Formation of Incision Complex in GG-NER
- RNA Polymerase II Pre-transcription Events
- Formation of TC-NER Pre-Incision Complex
- Transcription-Coupled Nucleotide Excision Repair (TC-NER)
- Dual incision in TC-NER
- Gap-filling DNA repair synthesis and ligation in TC-NER
- TP53 Regulates Transcription of DNA Repair Genes
- Cyclin E associated events during G1/S transition
- Cyclin D associated events in G1
- Cyclin A/B1/B2 associated events during G2/M transition
- Cyclin A:Cdk2-associated events at S phase entry
- mRNA Capping
- RNA Polymerase I Transcription Initiation
- RNA Polymerase I Promoter Escape
- RNA Polymerase II Promoter Escape
- RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
- RNA Polymerase I Transcription Termination
- RNA Polymerase II Transcription Initiation
- RNA Polymerase II Transcription Elongation
- RNA Polymerase II Transcription Initiation And Promoter Clearance
- RNA Pol II CTD phosphorylation and interaction with CE
- RUNX1 regulates transcription of genes involved in differentiation of HSCs
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MPG |
N-methylpurine DNA glycosylase |
- Recognition and association of DNA glycosylase with site containing an affected purine
- Cleavage of the damaged purine
- Displacement of DNA glycosylase by APEX1
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- Cisplatin
- Zinc
- Zinc acetate
- Zinc chloride
- Zinc sulfate, unspecified form
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MSH2 |
mutS homolog 2 |
- Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
- Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
- Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
- Defective Mismatch Repair Associated With MSH3
- Defective Mismatch Repair Associated With MSH2
- Defective Mismatch Repair Associated With MSH6
- TP53 Regulates Transcription of DNA Repair Genes
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- Colorectal cancer
- Mismatch repair deficiency, including: Hereditary non-polyposis colorectal cancer (HNPCC); Lynch syndrome; Muir-Torre syndrome; Turcot syndrome
- Ovarian cancer
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MTA1 |
metastasis associated 1 |
- HDACs deacetylate histones
- SUMOylation of transcription factors
- ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
- RNA Polymerase I Transcription Initiation
- Regulation of PTEN gene transcription
- Regulation of PTEN gene transcription
- Potential therapeutics for SARS
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