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CDC25A |
cell division cycle 25A |
- Transcription of E2F targets under negative control by DREAM complex
- Polo-like kinase mediated events
- Activation of ATR in response to replication stress
- Ub-specific processing proteases
- Cyclin E associated events during G1/S transition
- Cyclin A/B1/B2 associated events during G2/M transition
- Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
- Cyclin A:Cdk2-associated events at S phase entry
- Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
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CDC34 |
cell division cycle 34, ubiqiutin conjugating enzyme |
- Downstream TCR signaling
- FCERI mediated NF-kB activation
- CLEC7A (Dectin-1) signaling
- Synthesis of active ubiquitin: roles of E1 and E2 enzymes
- Antigen processing: Ubiquitination & Proteasome degradation
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CDH1 |
cadherin 1 |
- Degradation of the extracellular matrix
- Degradation of the extracellular matrix
- Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
- Integrin cell surface interactions
- Apoptotic cleavage of cell adhesion proteins
- Adherens junctions interactions
- RHO GTPases activate IQGAPs
- InlA-mediated entry of Listeria monocytogenes into host cells
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- Gastric cancer
- Penile cancer
- Nasopharyngeal cancer
- Breast cancer
- Hepatocellular carcinoma
- Thyroid cancer
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CDH5 |
cadherin 5 |
- Adherens junctions interactions
- VEGFR2 mediated vascular permeability
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CDK1 |
cyclin dependent kinase 1 |
- MAPK3 (ERK1) activation
- E2F-enabled inhibition of pre-replication complex formation
- Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
- Golgi Cisternae Pericentriolar Stack Reorganization
- Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes
- APC/C:Cdc20 mediated degradation of Cyclin B
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A
- Regulation of APC/C activators between G1/S and early anaphase
- Phosphorylation of the APC/C
- Phosphorylation of Emi1
- Condensation of Prophase Chromosomes
- MASTL Facilitates Mitotic Progression
- Resolution of Sister Chromatid Cohesion
- Condensation of Prometaphase Chromosomes
- Regulation of PLK1 Activity at G2/M Transition
- Activation of NIMA Kinases NEK9, NEK6, NEK7
- Initiation of Nuclear Envelope (NE) Reformation
- Nuclear Pore Complex (NPC) Disassembly
- Loss of Nlp from mitotic centrosomes
- Recruitment of mitotic centrosome proteins and complexes
- Loss of proteins required for interphase microtubule organization from the centrosome
- Recruitment of NuMA to mitotic centrosomes
- Depolymerisation of the Nuclear Lamina
- Anchoring of the basal body to the plasma membrane
- MAPK6/MAPK4 signaling
- Ovarian tumor domain proteases
- TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
- Regulation of TP53 Degradation
- Mitotic Prophase
- G1/S-Specific Transcription
- Cyclin A/B1/B2 associated events during G2/M transition
- Cyclin A/B1/B2 associated events during G2/M transition
- G2/M DNA replication checkpoint
- Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
- The role of GTSE1 in G2/M progression after G2 checkpoint
- AURKA Activation by TPX2
- Transcriptional regulation by RUNX2
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- Indirubin-3'-monoxime
- Olomoucine
- Hymenialdisine
- SU9516
- Alvocidib
- Alsterpaullone
- Seliciclib
- AT-7519
- Fostamatinib
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CEACAM1 |
CEA cell adhesion molecule 1 |
- Fibronectin matrix formation
- Cell surface interactions at the vascular wall
- Neutrophil degranulation
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- Technetium Tc-99m arcitumomab
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CEBPB |
CCAAT enhancer binding protein beta |
- Senescence-Associated Secretory Phenotype (SASP)
- Senescence-Associated Secretory Phenotype (SASP)
- ATF4 activates genes in response to endoplasmic reticulum stress
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional regulation of white adipocyte differentiation
- Transcriptional Regulation by VENTX
- Transcriptional regulation of granulopoiesis
- Response of EIF2AK4 (GCN2) to amino acid deficiency
- Response of EIF2AK4 (GCN2) to amino acid deficiency
- Response of EIF2AK1 (HRI) to heme deficiency
- Response of EIF2AK1 (HRI) to heme deficiency
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CEND1 |
cell cycle exit and neuronal differentiation 1 |
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CFL1 |
cofilin 1 |
- Platelet degranulation
- Regulation of actin dynamics for phagocytic cup formation
- EPHB-mediated forward signaling
- Sema3A PAK dependent Axon repulsion
- RHO GTPases Activate ROCKs
- Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
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- Dodecyldimethylamine N-oxide
- Copper
- Artenimol
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CLNK |
cytokine dependent hematopoietic cell linker |
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CLTA |
clathrin light chain A |
- Entry of Influenza Virion into Host Cell via Endocytosis
- Retrograde neurotrophin signalling
- Retrograde neurotrophin signalling
- Gap junction degradation
- Formation of annular gap junctions
- MHC class II antigen presentation
- EPH-ephrin mediated repulsion of cells
- Lysosome Vesicle Biogenesis
- Recycling pathway of L1
- Recycling pathway of L1
- WNT5A-dependent internalization of FZD4
- WNT5A-dependent internalization of FZD2, FZD5 and ROR2
- Cargo recognition for clathrin-mediated endocytosis
- Clathrin-mediated endocytosis
- VLDLR internalisation and degradation
- LDL clearance
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CLTCL1 |
clathrin heavy chain like 1 |
- Gap junction degradation
- Formation of annular gap junctions
- EPH-ephrin mediated repulsion of cells
- Cargo recognition for clathrin-mediated endocytosis
- Clathrin-mediated endocytosis
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CMTM8 |
CKLF like MARVEL transmembrane domain containing 8 |
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CNOT9 |
CCR4-NOT transcription complex subunit 9 |
- Deadenylation of mRNA
- Activation of anterior HOX genes in hindbrain development during early embryogenesis
- TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
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CNTN2 |
contactin 2 |
- L1CAM interactions
- NCAM1 interactions
- NrCAM interactions
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COL9A3 |
collagen type IX alpha 3 chain |
- Collagen degradation
- Collagen biosynthesis and modifying enzymes
- Signaling by PDGF
- Assembly of collagen fibrils and other multimeric structures
- Integrin cell surface interactions
- ECM proteoglycans
- NCAM1 interactions
- Collagen chain trimerization
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- Multiple epiphyseal dysplasia (MED)
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CRK |
CRK proto-oncogene, adaptor protein |
- ARMS-mediated activation
- ARMS-mediated activation
- Downstream signal transduction
- Regulation of actin dynamics for phagocytic cup formation
- p130Cas linkage to MAPK signaling for integrins
- VEGFA-VEGFR2 Pathway
- PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
- MET activates RAP1 and RAC1
- MET receptor recycling
- Regulation of signaling by CBL
- FCGR3A-mediated phagocytosis
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CSRP1 |
cysteine and glycine rich protein 1 |
- MTF1 activates gene expression
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CTNNB1 |
catenin beta 1 |
- Degradation of beta-catenin by the destruction complex
- Beta-catenin phosphorylation cascade
- TCF dependent signaling in response to WNT
- Formation of the beta-catenin:TCF transactivating complex
- Formation of the beta-catenin:TCF transactivating complex
- LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
- Apoptotic cleavage of cell adhesion proteins
- Deactivation of the beta-catenin transactivating complex
- Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
- Ca2+ pathway
- Adherens junctions interactions
- Binding of TCF/LEF:CTNNB1 to target gene promoters
- Disassembly of the destruction complex and recruitment of AXIN to the membrane
- Disassembly of the destruction complex and recruitment of AXIN to the membrane
- VEGFR2 mediated vascular permeability
- Myogenesis
- Myogenesis
- Signaling by GSK3beta mutants
- S33 mutants of beta-catenin aren't phosphorylated
- S37 mutants of beta-catenin aren't phosphorylated
- S45 mutants of beta-catenin aren't phosphorylated
- T41 mutants of beta-catenin aren't phosphorylated
- RHO GTPases activate IQGAPs
- Transcriptional Regulation by VENTX
- InlA-mediated entry of Listeria monocytogenes into host cells
- RUNX3 regulates WNT signaling
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- Gastric cancer
- Colorectal cancer
- Endometrial Cancer
- Pilomatricoma; Epithelioma calcificans of Malherbe
- Thyroid cancer
- Hepatocellular carcinoma
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CTNND1 |
catenin delta 1 |
- Adherens junctions interactions
- VEGFR2 mediated vascular permeability
- InlA-mediated entry of Listeria monocytogenes into host cells
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