Search Results for: CHEK2

85 interactions involving CHEK2 - checkpoint kinase 2 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
STMN1 stathmin 1
  • Nuclear signaling by ERBB4
STRAP serine/threonine kinase receptor associated protein
  • Downregulation of TGF-beta receptor signaling
  • Downregulation of TGF-beta receptor signaling
TLR3 toll like receptor 3
  • Trafficking and processing of endosomal TLR
  • Toll Like Receptor 3 (TLR3) Cascade
  • TICAM1, RIP1-mediated IKK complex recruitment
  • RIP-mediated NFkB activation via ZBP1
  • TLR3 deficiency - HSE
  • UNC93B1 deficiency - HSE
  • TICAM1 deficiency - HSE
  • TRAF3 deficiency - HSE
  • TLR3-mediated TICAM1-dependent programmed cell death
  • TICAM1-dependent activation of IRF3/IRF7
  • TICAM1,TRAF6-dependent induction of TAK1 complex
USP39 ubiquitin specific peptidase 39
  • mRNA Splicing - Major Pathway
VHL von Hippel-Lindau tumor suppressor
  • Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
  • Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
  • SUMOylation of ubiquitinylation proteins
  • Neddylation
  • Replication of the SARS-CoV-1 genome
  • Replication of the SARS-CoV-2 genome
  • RHOBTB3 ATPase cycle
  • Antigen processing: Ubiquitination & Proteasome degradation
  • Renal cell carcinoma
  • von Hippel-Lindau syndrome
  • Congenital polycythemia; Familial erythrocytosis (ECYT)

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