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CEP57 and AARD
Data Source:
BioGRID
(two hybrid)
CEP57
AARD
Description
centrosomal protein 57
alanine and arginine rich domain containing protein
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Golgi Apparatus
Centrosome
Cytosol
Microtubule
Molecular Function
Protein Binding
Microtubule Binding
Fibroblast Growth Factor Binding
Protein Homodimerization Activity
Gamma-tubulin Binding
Protein Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Spermatid Development
Fibroblast Growth Factor Receptor Signaling Pathway
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Microtubule Anchoring
Protein Homooligomerization
Ciliary Basal Body-plasma Membrane Docking
Lung Development
Pathways
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Drugs
Diseases
GWAS
Cognitive ability (MTAG) (
29186694
)
Erosive tooth wear (severe vs non-severe) (
29898447
)
Feeling worry (
29500382
)
Intelligence (MTAG) (
29326435
)
Rheumatoid arthritis (
30423114
24390342
)
Triglyceride levels x loop diuretics use interaction (
31806883
)
Interacting Genes
47 interacting genes:
AARD
ABI2
APP
ATPAF2
CCDC136
CCDC138
CCDC185
CCHCR1
CEP63
DEUP1
DISC1
FBXL3
FGF2
GCC1
HSF2BP
KDM1A
KLC4
KRT13
KRT15
KRT31
KRT4
KRT40
KRT75
KRT8
KRT83
KRT86
LMO3
MAGEA2
MAGEA2B
MEGF10
MIA2
MYC
OIP5
PKN1
PPP1R13B
RABEP1
RALBP1
RASSF10
SH3BP5L
SPDEF
TEX12
TFIP11
TSGA10
TSPYL4
TXLNA
TXLNB
UIMC1
15 interacting genes:
CENPQ
CEP57
GRIPAP1
KIAA0753
KRT24
KRT27
LMO4
MAGEB4
NTAQ1
STX1A
STX2
STX5
TFIP11
TSGA10
VPS37C
Entrez ID
9702
441376
HPRD ID
16261
18830
Ensembl ID
ENSG00000166037
ENSG00000205002
Uniprot IDs
Q86XR8
B2RU19
Q4LEZ3
PDB IDs
4L0R
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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