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RBM48 and RAB27A
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
RBM48
RAB27A
Description
RNA binding motif protein 48
RAB27A, member RAS oncogene family
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Photoreceptor Outer Segment
Extracellular Region
Lysosome
Late Endosome
Golgi Apparatus
Cytosol
Apical Plasma Membrane
Secretory Granule
Dendrite
Secretory Granule Membrane
Multivesicular Body Membrane
Weibel-Palade Body
Melanosome Membrane
Specific Granule Lumen
Melanosome
Extracellular Exosome
Exocytic Vesicle
Molecular Function
RNA Binding
Protein Binding
GTPase Activity
Protein Binding
GTP Binding
GDP Binding
Protein Domain Specific Binding
Myosin V Binding
Biological Process
Protein Targeting
Exocytosis
Blood Coagulation
Positive Regulation Of Gene Expression
Antigen Processing And Presentation
Melanocyte Differentiation
Melanosome Localization
Melanosome Transport
Multivesicular Body Organization
Neutrophil Degranulation
Cytotoxic T Cell Degranulation
Natural Killer Cell Degranulation
Positive Regulation Of Exocytosis
Synaptic Vesicle Transport
Positive Regulation Of Phagocytosis
Multivesicular Body Sorting Pathway
Complement-dependent Cytotoxicity
Positive Regulation Of Regulated Secretory Pathway
Positive Regulation Of Reactive Oxygen Species Biosynthetic Process
Positive Regulation Of Constitutive Secretory Pathway
Exosomal Secretion
Pathways
Insulin processing
Neutrophil degranulation
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
Other phagocyte defects, including the following eight diseases: Chediak-Higashi syndrome; Griscelli syndrome, type 1 (GS1); Griscelli syndrome, type 2 (GS2); Griscelli syndrome, type 3 (GS3); beta-actin deficiency; Neutrophil-specific granule deficiency; Myeloperoxidase deficiency; Glucose 6-phosphate dehydrogenase deficiency; Shwachman syndrome
GWAS
Idiopathic dilated cardiomyopathy (
29495422
)
Fractional exhaled nitric oxide levels (
25431337
)
Glioma (
30714141
)
Interacting Genes
73 interacting genes:
AMOT
ANXA7
APLP1
ARMC7
ATPAF2
BID
BTBD2
C11orf49
CCDC106
CCDC57
CDK5RAP2
CDKN1A
CDKN2C
COX17
COX5B
EIF1AD
ERH
FAM118B
FAM90A1
FXYD6
GADD45G
GLYAT
GSE1
GSTO1
GYS1
HSF2BP
HSPB1
HSPB3
ID2
JMY
KIF9
KPNA2
MAFG
MAP7D1
MLH1
MLLT3
MNAT1
MPHOSPH6
NTAQ1
NUDT21
OSGEP
PAFAH1B3
PCDHA4
PIBF1
PNP
POLR1C
PPP1R8
PRG2
PRKAB2
PSMD11
RAB27A
RAD51D
RFC5
RPA2
S100Z
SAT1
SCNM1
SERPINB9
SH3GL3
SMN1
SPRED2
SULT1E1
TAF9
TBC1D22B
TEKT4
TK1
TNFSF10
TRDMT1
TRIB3
TSR2
VIM
WDR33
ZNF24
28 interacting genes:
ADRB2
APP
CEP126
COPS6
EEF1A1
ERG28
EXPH5
GDF9
GDI1
GZMB
LRIF1
MLPH
MYO5A
MYRIP
RABGGTB
RBM48
RIMS1
RIMS2
RPH3A
RPH3AL
STX1A
SYTL1
SYTL2
SYTL3
SYTL4
SYTL5
UNC13D
ZBTB16
Entrez ID
84060
5873
HPRD ID
13173
04845
Ensembl ID
ENSG00000127993
ENSG00000069974
Uniprot IDs
Q5RL73
A2RU94
P51159
PDB IDs
6HUF
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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