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CEP70 and PRPF31
Data Source:
BioGRID
(two hybrid, two hybrid, two hybrid)
CEP70
PRPF31
Description
centrosomal protein 70
pre-mRNA processing factor 31
Image
No pdb structure
GO Annotations
Cellular Component
Centrosome
Cytosol
Nucleus
Nucleoplasm
U2-type Spliceosomal Complex
U4 SnRNP
U4atac SnRNP
Cajal Body
Nuclear Speck
U4/U6 X U5 Tri-snRNP Complex
U2-type Precatalytic Spliceosome
Precatalytic Spliceosome
MLL1 Complex
Spliceosomal Tri-snRNP Complex
Molecular Function
Protein Binding
Identical Protein Binding
Gamma-tubulin Binding
RNA Binding
Protein Binding
U4 SnRNA Binding
U4atac SnRNA Binding
Identical Protein Binding
Ribonucleoprotein Complex Binding
SnRNP Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Regulation Of Microtubule Cytoskeleton Organization
Ciliary Basal Body-plasma Membrane Docking
Spliceosomal Tri-snRNP Complex Assembly
MRNA Splicing, Via Spliceosome
SnoRNA Localization
Ribonucleoprotein Complex Localization
Pathways
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
mRNA Splicing - Major Pathway
Drugs
Diseases
Retinitis pigmentosa (RP)
GWAS
Exhaled carbon monoxide levels in smokers with chronic obstructive pulmonary disease (
29631575
)
Male-pattern baldness (
28196072
)
Change in HbA1c levels in response to metformin treatment in type 2 diabetes (
29650774
)
Interacting Genes
242 interacting genes:
ABT1
AGBL2
AKAP17A
ARHGEF3
ARMCX1
ATP5PO
ATXN7
BARD1
BAZ2B
BEX2
BRD1
BRMS1
BRMS1L
BRPF1
BYSL
C1orf35
C7orf25
C8orf33
CARD9
CAVIN3
CBX8
CCDC187
CCDC85B
CDC37
CDC73
CDCA7L
CEP57L1
CFAP53
CLPB
COIL
CWF19L2
DAXX
DAZAP2
DDX41
DDX6
DNAJB11
DNTTIP2
DVL3
EAF1
EBNA1BP2
EIF3D
ELOA
ELOA2
EMD
EMP1
ENKD1
ERCC3
FAM118B
FAM124A
FAM133A
FAM13C
FAM161A
FAM161B
FAM214B
FAM90A1
GADD45GIP1
GAS8
GATAD2B
GCC1
GEM
GLYCTK
GPATCH2L
GPATCH4
GPX7
GSE1
HAUS1
HDAC4
HDAC6
HIC2
HMGB4
HOXB5
HOXC8
HSPD1
IK
INO80B
INPP5J
IPCEF1
IQCE
IQUB
ITPKB
KANK2
KANSL1
KAT14
KAT5
KAT7
KDM1A
KRI1
KRT31
LAMTOR5
LCOR
LENG1
LENG8
LIN37
LNX1
MAB21L2
MAGOH
MBD3
MCM10
MCRS1
MEST
METTL17
MFAP1
MKRN3
MRPL44
NEBL
NIPSNAP3A
NKAP
NKAPD1
NOL12
NOP2
NOP53
NOXA1
NRIP1
NTAQ1
NUSAP1
ODAD4
PAM16
PIBF1
PIMREG
PKN1
PLA2G2A
PPFIA1
PPIG
PPP1R16B
PPP1R18
PRKRIP1
PRPF18
PRPF3
PRPF31
PSMA1
PSORS1C2
RASSF10
RBM10
RCOR3
RHPN1
RNF169
RNF6
RPL13
SCNM1
SEC14L1
SERPINH1
SETD5
SFR1
SH2D4A
SLU7
SMARCE1
SNRPD2
SNW1
SOD2
SPANXN3
SRGN
SSX3
STK25
STMN2
SUV39H1
SUV39H2
SYT17
SYTL4
SYTL5
TAF1D
TBC1D22B
TBC1D30
TCAF1
TCEANC
TEAD4
TLK2
TRAF3IP3
TRIM29
TRIM3
TRIM42
TSFM
TSGA10IP
TSHZ3
TTLL10
TXLNB
TXN2
USP2
UTP11
UTP14A
UTP14C
UTP25
UTP3
VXN
WT1
YJU2
ZBTB16
ZBTB24
ZBTB4
ZBTB47
ZBTB48
ZBTB49
ZBTB8A
ZCCHC10
ZFC3H1
ZFHX3
ZFP1
ZFP91
ZGPAT
ZNF136
ZNF140
ZNF148
ZNF165
ZNF169
ZNF17
ZNF20
ZNF202
ZNF227
ZNF239
ZNF264
ZNF266
ZNF302
ZNF329
ZNF35
ZNF366
ZNF408
ZNF410
ZNF417
ZNF426
ZNF433
ZNF439
ZNF490
ZNF491
ZNF555
ZNF557
ZNF572
ZNF574
ZNF578
ZNF587
ZNF599
ZNF607
ZNF648
ZNF669
ZNF688
ZNF696
ZNF775
ZNF777
ZNF785
ZNF835
ZNF860
ZSCAN12
ZSCAN21
ZSCAN23
135 interacting genes:
ASB15
BHLHB9
BICD2
C1QTNF1
CALCOCO2
CAPNS2
CARD14
CBY2
CCDC106
CCDC136
CCDC33
CCDC57
CCDC70
CCNDBP1
CDC23
CDCA7L
CDR2L
CEP70
CYSRT1
DVL2
DVL3
EFEMP2
EVI5
FANCA
FANCC
FASTK
FLACC1
FSD2
FXR1
GOLGA2
GOLGA6L9
HAP1
HES7
HNRNPH2
HNRNPK
HOOK2
HSF2BP
JAKMIP2
KANK2
KCTD6
KHDRBS2
KHDRBS3
KIFC3
KRT15
KRT31
KRT34
KRT35
KRT40
KRTAP1-1
KRTAP1-3
KRTAP10-1
KRTAP10-3
KRTAP10-8
KRTAP10-9
KRTAP19-5
KRTAP4-11
KRTAP6-3
LBX1
LDOC1
LHX8
LURAP1
LZTS2
MDFI
MEIS3
MEOX2
MID2
MIPOL1
MKRN3
MTUS2
NCAPH2
NCKIPSD
NOTCH2NLA
PAK5
PDE4DIP
PHC2
PHF5A
PICK1
PLEKHG4
PNMA1
PNMA2
PNMA3
PPIH
PPP1R16A
PPP2R3C
PRDM14
PRICKLE1
PRPF3
PSTPIP1
RACK1
RBAK
RBM25
RBM4
RBMX
RBMY1A1
RBMY1F
RBMY1J
REL
RINT1
RUNDC3A
SIAH1
SLAIN1
SNRNP200
SRSF3
SSX2IP
STX11
TADA2A
TFIP11
TLE5
TMCC2
TP53BP2
TRIM14
TRIM23
TRIM27
TRIM41
TSGA10
UBXN11
USH1G
USP15
VWC2
ZFP64
ZFP69B
ZNF24
ZNF250
ZNF408
ZNF417
ZNF473
ZNF48
ZNF587
ZNF668
ZNF71
ZNF774
ZNF792
ZNF837
ZRANB1
ZSCAN22
Entrez ID
80321
26121
HPRD ID
16779
05917
Ensembl ID
ENSG00000114107
ENSG00000105618
Uniprot IDs
A0A140VJG2
B7Z2D2
Q8NHQ1
Q8WWY3
PDB IDs
2OZB
3JCR
3SIU
3SIV
5O9Z
6AH0
6AHD
6QW6
6QX9
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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