TUBG1 and RND2

Data Source:
BioGRID (affinity chromatography technology)

		TUBG1	RND2
Description		tubulin gamma 1	Rho family GTPase 2
Image			No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome Gamma-tubulin Complex Nucleus Cytoplasm Centrosome Spindle Polar Microtubule Cytosol Microtubule Recycling Endosome Mitotic Spindle Microtubule	Acrosomal Membrane Early Endosome Cytoskeleton Plasma Membrane Cell Cortex Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle
	Molecular Function	GTPase Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding Identical Protein Binding	GTPase Activity Protein Binding GTP Binding Protein Kinase Binding Protein N-terminus Binding
	Biological Process	Mitotic Sister Chromatid Segregation G2/M Transition Of Mitotic Cell Cycle Meiotic Spindle Organization Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule Nucleation Mitotic Spindle Organization Regulation Of G2/M Transition Of Mitotic Cell Cycle Cytoplasmic Microtubule Organization Ciliary Basal Body-plasma Membrane Docking	Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Signal Transduction Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Cell Migration Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Collateral Sprouting
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs		Vinblastine
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549)	Coronary artery disease ( 29212778)
Interacting Genes		28 interacting genes: APP BRCA1 CENPJ CNTN2 CUL4A DDX41 IKBKG KIF14 KRT18 KRT19 MARK4 NAPG NDE1 PCNT PIK3R1 PLK1 PXN RACGAP1 RACK1 RASSF1 RNF19A RPGR SPATC1 TUBA1B TUBA3C TUBB4B TUBGCP3 TUBGCP4	6 interacting genes: ARHGAP5 FNBP1 MEOX2 RACGAP1 UBXN11 VPS4A
Entrez ID		7283	8153
HPRD ID		01853	03332
Ensembl ID		ENSG00000131462	ENSG00000108830
Uniprot IDs		P23258	P52198
PDB IDs		1Z5V 1Z5W 3CB2 6V5V 6V6S
Enriched GO Terms of Interacting Partners?
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