TUBB2A and CHGB

Data Source:
BioGRID (two hybrid)

		TUBB2A	CHGB
Description		tubulin beta 2A class IIa	chromogranin B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Extracellular Exosome Extracellular Vesicle	Extracellular Space Endoplasmic Reticulum Lumen Secretory Granule
	Molecular Function	GTPase Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding	Hormone Activity Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Neuron Migration	Signal Transduction Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Gap junction assembly MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) Recruitment of NuMA to mitotic centrosomes Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Post-chaperonin tubulin folding pathway Recycling pathway of L1 Recycling pathway of L1 Hedgehog 'off' state Cilium Assembly Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint Carboxyterminal post-translational modifications of tubulin Carboxyterminal post-translational modifications of tubulin HCMV Early Events Assembly and cell surface presentation of NMDA receptors Activation of AMPK downstream of NMDARs Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs		CYT997 Phenethyl Isothiocyanate
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Red cell distribution width ( 32888494 27863252)	Metabolite levels ( 23823483) Uterine fibroid number (single vs multiple) ( 30196971)
Interacting Genes		27 interacting genes: ACD ARL15 ARNT CHGB DISC1 DUX4 HDAC6 HGS HMMR LAMA4 LINC01554 PAFAH1B3 POT1 PSMD11 PTPRS RABAC1 RIC8A RPA2 RPLP1 SAT1 SDC3 SERPINB9 TERF1 TK1 TNIK TPT1 UPF2	34 interacting genes: ACACA ANXA7 APP ATXN2 CBFB CCDC92 CDKN1A FGFR3 LRRK1 LRRK2 MARK3 MFHAS1 MGLL MOGS OGG1 PKN2 POLD1 POLR2E PRAG1 PTEN RAC2 RAP1B RCC1 RXRG S100A8 SAFB2 SLC25A6 TAZ TK1 TUBB2A TWF2 UBQLN1 UBTF YLPM1
Entrez ID		7280	1114
HPRD ID			07512
Ensembl ID		ENSG00000137267	ENSG00000089199
Uniprot IDs		Q13885	P05060
PDB IDs
Enriched GO Terms of Interacting Partners?
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