TBCE and EIF2B2

Data Source:
BioGRID (two hybrid)

		TBCE	EIF2B2
Description		tubulin folding cofactor E	eukaryotic translation initiation factor 2B subunit beta
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GO Annotations	Cellular Component	Cytoplasm Microtubule	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 2B Complex
	Molecular Function	Protein Binding Alpha-tubulin Binding Chaperone Binding	Translation Initiation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding ATP Binding GTP Binding
	Biological Process	Microtubule Cytoskeleton Organization Protein Folding Tubulin Complex Assembly Post-chaperonin Tubulin Folding Pathway Mitotic Spindle Organization	Ovarian Follicle Development Translational Initiation Regulation Of Translational Initiation Central Nervous System Development Response To Heat Response To Glucose Oligodendrocyte Development Myelination Response To Peptide Hormone Regulation Of Catalytic Activity T Cell Receptor Signaling Pathway
Pathways		Post-chaperonin tubulin folding pathway	Recycling of eIF2:GDP
Drugs
Diseases		Hypoparathyroidism-retardation-dysmorphism syndrome; Sanjad-Sakati syndrome Kenny-Caffey syndrome	Leukoencephalopathy with vanishing white matter; Vanishing white matter disease; Childhood ataxia with diffuse central nervous system hypomyelination (CACH); Cree leukoencephalopathy (CLE)
GWAS		Adiposity ( 19557161) Blood protein levels ( 30072576) Household income (MTAG) ( 31844048)	Coronary artery disease ( 33020668) Mood instability ( 29187730) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		2 interacting genes: TBCD TUBA4A	12 interacting genes: APP C9orf72 CCT3 CSNK2A2 EIF2B1 EIF2B4 EIF2B5 EIF2S1 MRFAP1L1 NCK1 PCGF6 TET2
Entrez ID		6905	8892
HPRD ID		05381	05923
Ensembl ID		ENSG00000284770	ENSG00000119718
Uniprot IDs		A0A2R8Y6Q1 Q15813	P49770 Q53XC2
PDB IDs		4ICU 4ICV	6CAJ 6EZO 6K71 6K72 6O81 6O85 6O9Z
Enriched GO Terms of Interacting Partners?
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