PRDM1 and H3C15

  • Data Source:
  • BioGRID (enzymatic study)

PRDM1

H3C15

Description PR/SET domain 1 H3 clustered histone 15
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs) ( 23648065)
  • Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065)
  • Carboplatin disposition in epthelial ovarian cancer ( 29367611)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 21102463)
  • Diastolic blood pressure ( 30224653)
  • Monobrow ( 27182965)
  • Multiple myeloma ( 27363682)
  • Response to (pegylated) interferon in HBeAG-positive hepatitis B ( 30715261)
  • Sjögren's syndrome ( 24097067)
  • Systemic lupus erythematosus ( 27399966 23273568 26502338 28714469 19838193 19838195)
  • Systemic sclerosis ( 28314753)
  • Triglyceride levels ( 32203549)
Interacting Genes 10 interacting genes: ATXN1 H1-1 H3C15 IKZF3 IRF4 KDM1A PIAS1 TLE1 TLE2 TLE5 18 interacting genes: ANP32A CBX5 DNTTIP2 EHMT2 GTF3C4 HDAC9 KDM5A KDM5C LALBA MECP2 NASP PADI4 PRDM1 PRMT6 SETDB1 SUV39H1 UBR7 UHRF1
Entrez ID 639 333932
HPRD ID 04572
Ensembl ID ENSG00000057657 ENSG00000203852
Uniprot IDs A0A3B3IU23 B4DW27 O75626 Q5T4E8 Q71DI3
PDB IDs 3DAL 2IIJ 2X4W 2X4X 2X4Y 3AV1 3DB3 3MO8 3QO2 3R93 4MZF 4MZG 4MZH 4OUC 5B0Y 5B0Z 5B40 5BO0 5CIU 5VAC 6ACE 6FML 6T79 6T7A 6T7B 6T7C 6T7D 6X59 6X5A 6XJD 6Y5D 6Y5E 7BQZ 7BU9 7JO9 7JOA
Enriched GO Terms of Interacting Partners?
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