RNASEL and ABCE1

Data Source:
HPRD (in vitro)

		RNASEL	ABCE1
Description		ribonuclease L	ATP binding cassette subfamily E member 1
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GO Annotations	Cellular Component	Cellular_component Mitochondrial Matrix Cytosol Nuclear Matrix	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane
	Molecular Function	RNA Binding Endoribonuclease Activity Ribonuclease Activity Protein Kinase Activity Protein Binding ATP Binding RRNA Binding Ribonucleoprotein Complex Binding Metal Ion Binding	Iron Ion Binding Protein Binding ATP Binding ATPase Activity Ribosomal Small Subunit Binding Endoribonuclease Inhibitor Activity
	Biological Process	RRNA Processing RNA Processing MRNA Processing Protein Phosphorylation Regulation Of MRNA Stability Negative Regulation Of Viral Genome Replication Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Glucose Import Defense Response To Virus Type I Interferon Signaling Pathway Regulation Of Type I Interferon-mediated Signaling Pathway RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Ribosomal Subunit Export From Nucleus Translational Initiation Translational Termination Viral Process Defense Response To Virus Regulation Of Type I Interferon-mediated Signaling Pathway Negative Regulation Of Endoribonuclease Activity
Pathways		OAS antiviral response Interferon alpha/beta signaling	OAS antiviral response Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Morning vs. evening chronotype ( 26835600) Multiple sclerosis ( 23412934)	Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Malaria ( 31844061) Subcortical volume (MOSTest) ( 32665545) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		3 interacting genes: ABCE1 AR TCF12	3 interacting genes: EIF3J RNASE2 RNASEL
Entrez ID		6041	6059
HPRD ID		01590	03132
Ensembl ID		ENSG00000135828	ENSG00000164163
Uniprot IDs		Q05823	P61221
PDB IDs		1WDY 4G8K 4G8L 4OAU 4OAV	6ZME 6ZVJ 7A09
Enriched GO Terms of Interacting Partners?
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