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UBQLN4 and BAG6
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(two hybrid)
UBQLN4
BAG6
Description
ubiquilin 4
BAG cochaperone 6
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Autophagosome
Endoplasmic Reticulum Membrane
Cytosol
Cytoplasmic Vesicle
Nuclear Proteasome Complex
Cytosolic Proteasome Complex
Protein-containing Complex
Perinuclear Region Of Cytoplasm
Site Of DNA Damage
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Intracellular Membrane-bounded Organelle
Extracellular Exosome
BAT3 Complex
Molecular Function
Protein Binding
Polyubiquitin Modification-dependent Protein Binding
K48-linked Polyubiquitin Modification-dependent Protein Binding
Identical Protein Binding
Signaling Receptor Binding
Protein Binding
Polyubiquitin Modification-dependent Protein Binding
Ubiquitin Protein Ligase Binding
Ribosome Binding
Misfolded Protein Binding
Proteasome Binding
Ubiquitin-specific Protease Binding
Biological Process
DNA Repair
Ubiquitin-dependent Protein Catabolic Process
Autophagy
Cellular Response To DNA Damage Stimulus
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Autophagosome Maturation
Negative Regulation Of Double-strand Break Repair Via Homologous Recombination
Kidney Development
Immune Response-activating Cell Surface Receptor Signaling Pathway
Chromatin Organization
Ubiquitin-dependent Protein Catabolic Process
Apoptotic Process
Synaptonemal Complex Assembly
Spermatogenesis
Brain Development
Proteasomal Protein Catabolic Process
Internal Peptidyl-lysine Acetylation
Natural Killer Cell Activation
Cell Differentiation
Lung Development
Ubiquitin-dependent ERAD Pathway
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Negative Regulation Of Proteolysis
Regulation Of Embryonic Development
Protein Stabilization
Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
ER-associated Misfolded Protein Catabolic Process
Tail-anchored Membrane Protein Insertion Into ER Membrane
Positive Regulation Of ERAD Pathway
Maintenance Of Unfolded Protein Involved In ERAD Pathway
Protein Localization To Cytosolic Proteasome Complex Involved In ERAD Pathway
Pathways
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS
Body fat distribution (leg fat ratio) (
30664634
)
Body fat distribution (trunk fat ratio) (
30664634
)
Body mass index (
29273807
)
Crohn's disease (
28067908
)
General risk tolerance (MTAG) (
30643258
)
Inflammatory bowel disease (
28067908
23128233
)
Asthma (
31619474
)
Asthma (childhood onset) (
31619474
)
Asthma and major depressive disorder (
31619474
)
Autism spectrum disorder or schizophrenia (
28540026
)
Blood protein levels (
28240269
)
Height (
28552196
)
Inflammatory bowel disease (
28067908
)
Malaria (
31844061
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Medication use (HMG CoA reductase inhibitors) (
31015401
)
Schizophrenia (
23894747
)
Small cell lung carcinoma (
28604730
)
Smoking status (ever vs never smokers) (
30643258
)
Ulcerative colitis (
28067908
)
Interacting Genes
161 interacting genes:
ADAM33
ADPGK
AGR2
ANKRD13D
AREG
ARL4C
ATP5IF1
ATP5MK
ATXN1
BAG6
BPIFA1
C11orf49
C1orf94
C1QTNF1
CACNA1G
CCDC107
CCDC134
CCDC136
CCDC14
CCDC33
CCL21
CD99
CDSN
CEND1
COL8A1
COPB1
CPSF6
CRIPT
CSTF2
CSTF2T
CTSB
CYB5R1
DAZAP2
DKK3
DMPK
DNAJB11
DTX2
EAPP
EDN1
EEF1A1
EFEMP2
ELF5
EPDR1
ERP27
ERP29
FA2H
FGFBP1
FKBP2
FKBP7
FZD7
GABRD
GDI1
GJA1
GJA5
GJC1
GKAP1
GPX7
HAVCR1
HGS
HK2
HSPA13
HSPA5
IGFBP6
IGHM
IGLC1
IMMT
IMPDH2
ITPRIPL1
KLHL26
KLHL42
LAT2
MDK
MDM2
MIEF2
MIF4GD
MLLT6
MOAP1
MTNR1B
MYDGF
NAE1
NME3
NOMO1
NOMO3
NOTCH2NLA
NPHP1
NPPA
NXF1
OAT
ORC5
PBXIP1
PCDH17
PCDH8
PDIA5
PDLIM7
PELI2
PICK1
PIN1
PIP4K2B
PLAAT3
PMEPA1
PNMA1
PPIB
PPIC
PRL
PRPF40A
PTN
PTPRN
PTPRN2
QSOX1
RAD23A
RAI2
RBM10
RIC8A
RNF11
RNPS1
ROBO2
RPN1
RSRC2
RUNX1T1
RXRA
SCAF1
SCG2
SCG5
SCMH1
SEMG1
SERPINE1
SERPINH1
SERPINI2
SMAD3
SMAD9
SMARCB1
SPAG8
SPINT1
SPP1
SRGN
SRSF2
STAM2
STMN1
SUPT20H
TFF1
TGFB1I1
TNFRSF14
TNRC6B
TRAF2
TRIB2
TRIM32
UBC
UBQLN1
UBQLN2
UBR7
UNC119
UROS
VIP
WAC
YWHAQ
ZBTB22
ZDHHC3
ZFPM2
ZG16
ZG16B
ZNF205
118 interacting genes:
ACVR1B
AMFR
AMTN
ANTKMT
ANXA7
APBB1IP
ARPC3
ATN1
ATXN2
B2M
C1QA
CD93
CDK16
CDK4
CDK5
CDKN1A
CDSN
CHN2
CILK1
CLU
CSNK2B
CSTF2
CTAG1A
CTAG1B
CTCFL
CTSB
CTSE
CTSL
CXCL8
CYSRT1
DMKN
DNAJB11
DPT
EDN1
EFEMP1
EFEMP2
ELP1
EP300
FAM9B
FAS
FKBP2
FZD4
GADD45A
GET4
GLRA2
GOLGA6L9
GSK3B
HSPA13
HSPA8
IGF2
IGFBP5
IMMT
IQCG
KLHL12
KPNA2
LBP
MAPK6
MEST
MTNR1A
MYDGF
NBL1
NCR3
NDUFA6
NDUFB11
NOMO1
NPY
NR1H2
PELP1
PIN1
PLA2G2A
PLK1
PLPP2
PLPPR3
POLR2J
PRKAR1B
PRMT2
PRNP
PRPF40A
PTH
PTN
PTPN12
RAB8A
RAC1
RCC1
RCN2
REG1B
RNF126
S100A4
SDC2
SEC61A1
SEC61B
SERPING1
SERPINH1
SERPINI2
SETDB1
SGTA
SMN1
SPP1
SRGN
STX5
TAC1
TDGF1
TENT5A
TFCP2
TK1
TOMM20
TP53
TP63
TTR
UBL4B
UBL7
UBQLN1
UBQLN2
UBQLN4
USP13
VAMP2
XRN1
ZFYVE9
Entrez ID
56893
7917
HPRD ID
05670
00808
Ensembl ID
ENSG00000160803
ENSG00000204463
Uniprot IDs
B4DZF6
Q59F94
Q9NRR5
A0A1U9X7A6
P46379
PDB IDs
1WX9
2N9P
4DWF
4EEW
4WWR
4X86
6AU8
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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