POLE4 and B4GALT4

Data Source:
HPRD (two hybrid)

		POLE4	B4GALT4
Description		DNA polymerase epsilon 4, accessory subunit	beta-1,4-galactosyltransferase 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex Epsilon DNA Polymerase Complex	Golgi Membrane Golgi Apparatus Integral Component Of Membrane Golgi Cisterna Membrane
	Molecular Function	DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Protein Heterodimerization Activity	N-acetyllactosamine Synthase Activity Galactosyltransferase Activity Metal Ion Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle DNA Replication Initiation Telomere Maintenance Via Semi-conservative Replication DNA Biosynthetic Process	Carbohydrate Metabolic Process Protein Glycosylation Membrane Lipid Metabolic Process Keratan Sulfate Biosynthetic Process Glycosylation
Pathways		Recognition of DNA damage by PCNA-containing replication complex PCNA-Dependent Long Patch Base Excision Repair Termination of translesion DNA synthesis HDR through Homologous Recombination (HRR) Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER DNA replication initiation Activation of the pre-replicative complex	Keratan sulfate biosynthesis N-Glycan antennae elongation
Drugs		Cladribine	N-Acetylglucosamine
Diseases
GWAS			Clozapine-induced cytotoxicity ( 25656473) Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042) Survival in pancreatic cancer ( 28470677)
Interacting Genes		7 interacting genes: HSPA13 NFYB POLE POLE2 POLE3 PRKAR1B UBE3A
Entrez ID		56655	8702
HPRD ID		16238	04930
Ensembl ID		ENSG00000115350	ENSG00000121578
Uniprot IDs		Q9NR33	B2RAZ5 B3KM35 O60513
PDB IDs
Enriched GO Terms of Interacting Partners?
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