TUBD1 and RFX5

Data Source:
BioGRID (affinity chromatography technology)

		TUBD1	RFX5
Description		tubulin delta 1	regulatory factor X5
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Centriole Cytosol Microtubule Cilium	Chromatin RNA Polymerase II Transcription Regulator Complex
	Molecular Function	GTPase Activity Structural Constituent Of Cytoskeleton GTP Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Multicellular Organism Development Cell Projection Organization Positive Regulation Of Smoothened Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs		Vinblastine
Diseases			Bare lymphocyte syndrome (BLS) type2 Combined immunodeficiencies (CIDs), including the following nine diseases: X-linked hyper IgM syndrome; CD40 deficiency hyper IgM syndrome; Purine nucleoside phosphorylase (PNP) deficiency; Omenn syndrome; MHC deficiency (HLA-class I); MHC deficiency (HLA-class II); Zap-70 deficiency; p56 Lck deficiency; CD8 deficiency
GWAS		C-reactive protein levels ( 30388399) Chronotype ( 30696823) Crohn's disease ( 28067908) Eosinophil counts ( 32888494) Eosinophil percentage of granulocytes ( 27863252) Hemoglobin levels ( 32327693) Inflammatory bowel disease ( 23128233) Mean reticulocyte volume ( 32888494) Monocyte count ( 29403010) Obesity-related traits ( 23251661) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 27863252 28957414) Systolic blood pressure ( 30578418)	Body mass index ( 26426971)
Interacting Genes		1 interacting genes: TOP1	5 interacting genes: APP CIITA HDAC2 RFXANK RFXAP
Entrez ID		51174	5993
HPRD ID		06297	03517
Ensembl ID		ENSG00000108423	ENSG00000143390
Uniprot IDs		Q9UJT1	P48382
PDB IDs			2KW3 3V30
Enriched GO Terms of Interacting Partners?
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