PAK2 and PPM1A

  • Data Source:
  • BioGRID (enzymatic study)

PAK2

PPM1A

Description p21 (RAC1) activated kinase 2 protein phosphatase, Mg2+/Mn2+ dependent 1A
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergic rhinitis ( 22036096)
  • Blond vs. brown/black hair color ( 30531825)
  • Chronotype ( 30696823)
  • Diastolic blood pressure ( 30224653)
  • Hair color ( 29662168)
  • Hip circumference adjusted for BMI ( 25673412)
  • Menarche (age at onset) ( 27182965)
  • Refractive error ( 32231278)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes 54 interacting genes: ABI1 ABI2 ABI3 ABL1 APP ARHGAP10 ARHGEF6 ARHGEF7 BRAF CASP3 CDC42 DOCK2 DST EIF4B EIF4G1 EP300 FYN GRB2 H4C6 HCK LCK LIMK1 LYN MAPK1 MAPK3 MKNK1 MYC MYL2 MYLK NCK1 NCK2 NPHP1 PACSIN3 PPM1A RAC1 RAC2 RAF1 RHOJ RIOK3 RPS6 SH3GL2 SH3KBP1 SH3PXD2A SH3RF1 SH3RF3 SNX33 SNX9 SORBS1 SORBS2 SORBS3 SRC SYN1 VIM YES1 37 interacting genes: AATK AKT1 ALK CACNA1A CACNA1B CACNA1C CDC42BPA CDC42BPB CTNNB1 DVL1 DVL2 DVL3 EEF2 EGFR ERBB2 ERBB3 ERBB4 FGFR2 GRM3 HSPB1 IGF1R KDR LMTK2 MSN NR4A1 PAK1 PAK2 PIK3R1 PLK3 PRKAA1 PRKCA PRKCD PTK7 ROR2 RPLP0 SMAD2 SMAD3
Entrez ID 5062 5494
HPRD ID 05428 16199
Ensembl ID ENSG00000180370 ENSG00000100614
Uniprot IDs A8K5M4 Q13177 A0A024R6A5 B2R8E4 P35813
PDB IDs 3PCS 1A6Q 3FXJ 3FXK 3FXL 3FXM 3FXO 4RA2 4RAF 4RAG 6B67
Enriched GO Terms of Interacting Partners?
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