KRT5 and KRT7

Data Source:
BioGRID (affinity chromatography technology)

		KRT5	KRT7
Description		keratin 5	keratin 7
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Intermediate Filament Membrane Keratin Filament Extracellular Exosome	Nucleus Cytoplasm Cytosol Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Scaffold Protein Binding	Protein Binding
	Biological Process	Cytoskeleton Organization Epidermis Development Keratinization Hemidesmosome Assembly Cornification	Viral Process Keratinization Cornification
Pathways		Type I hemidesmosome assembly Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs		Zinc Zinc acetate	Primaquine Verpasep caltespen
Diseases		Dowling-Degos disease Epidermolysis bullosa simplex, including: Epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM); Epidermolysis bullosa simplex, Koebner type (EBS-K); Epidermolysis bullosa simplex, Weber-Cockayne type (EBS-WC); Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP); Epidermolysis bullosa simplex with migratory circinate erythema; Epidermolysis bullosa simplex, recessive; Epidermolysis bullosa, lethal acantholytic
GWAS		Basal cell carcinoma ( 31174203 24403052 25855136 27539887) Cutaneous squamous cell carcinoma ( 32041948) Keratinocyte cancer (MTAG) ( 31174203) Non-melanoma skin cancer ( 29739929) Squamous cell carcinoma ( 31174203)	Blond vs. brown/black hair color ( 30531825) Diisocyanate-induced asthma ( 25918132)
Interacting Genes		25 interacting genes: ALOX12 ALOX12B APC DSP DST EVPL INCA1 KIFC3 KRT1 KRT14 KRT15 KRT16 KRT18 KRT19 KRT24 KRT25 KRT27 KRT28 KRT31 KRT35 KRT38 KRT40 PKP2 TCHP UBE3A	11 interacting genes: ATF7IP EGFR HMGB1 HSPA1A KDM1A KRT13 KRT17 KRT27 LAPTM5 LINC01554 UBE3A
Entrez ID		3852	3855
HPRD ID		01010	01014
Ensembl ID		ENSG00000186081	ENSG00000135480
Uniprot IDs		P13647	P08729
PDB IDs		3TNU 6JFV	4XIF
Enriched GO Terms of Interacting Partners?
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