IHO1 and ATP6V0D1

Data Source:
BioGRID (two hybrid)

		IHO1	ATP6V0D1
Description		interactor of HORMAD1 1	ATPase H+ transporting V0 subunit d1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome	Lysosomal Membrane Early Endosome Centrosome Endosome Membrane Membrane Vacuolar Proton-transporting V-type ATPase Complex Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Plasma Membrane Proton-transporting V-type ATPase Complex Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	DNA Recombination Homologous Chromosome Pairing At Meiosis Spermatogenesis Meiotic DNA Double-strand Break Formation Oogenesis Regulation Of Homologous Chromosome Segregation	Cellular Iron Ion Homeostasis Vacuolar Transport Vacuolar Acidification Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Cellular Response To Increased Oxygen Levels IRE1-mediated Unfolded Protein Response Cilium Assembly Phagosome Acidification Proton Transmembrane Transport
Pathways			ROS and RNS production in phagocytes XBP1(S) activates chaperone genes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs			Tiludronic acid
Diseases
GWAS			Blood protein levels ( 28240269) Disease progression in age-related macular degeneration ( 29346644) Empathy quotient ( 29527006) Medication use (thyroid preparations) ( 31015401) Refractive error ( 32231278)
Interacting Genes		78 interacting genes: ABI2 ABI3 ADAMTS12 AQP1 ARHGEF9 ATP6V0D1 BCL6 BOLA2 BOLA2B C1orf109 CARD9 CCDC120 CCDC57 CDC23 CFAP206 COX5B DGCR6 DVL2 DYNLL1 DYNLL2 EAF2 EFHC1 EXOC8 FAM124A FAM124B FANCG FANCL FASLG FHL3 FKBP6 GEM GLRX3 GLYCTK GOLGA2 GRAP2 GYS1 HEXIM2 HINFP IQUB KANK2 KIF9 KIFC3 KLC3 KLHL11 LMO2 LNX1 LONRF1 MAGEB4 MAGOHB MAPK9 MID2 MRFAP1L1 MVP MYO15B NEK6 NFKBID NGB PICK1 POLR1C PRKAB2 PRR34 RABGEF1 RAD51D RHOBTB3 RUNX1T1 SDCBP SMARCB1 STK25 TNS2 TRIM14 TRIM42 TTC19 USP2 USP20 ZGPAT ZKSCAN3 ZNF417 ZNF688	10 interacting genes: ADRB2 ATXN1 DMRT3 GATA1 IHO1 IKZF3 LIG4 RBPMS TLE5 TLX3
Entrez ID		339834	9114
HPRD ID		14172	06121
Ensembl ID		ENSG00000173421	ENSG00000159720
Uniprot IDs		B4DZP6 Q8IYA8	P61421 R4GN72
PDB IDs
Enriched GO Terms of Interacting Partners?
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