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IHO1 and USP2
Data Source:
BioGRID
(two hybrid)
IHO1
USP2
Description
interactor of HORMAD1 1
ubiquitin specific peptidase 2
Image
No pdb structure
GO Annotations
Cellular Component
Condensed Nuclear Chromosome
Nucleoplasm
Cytoplasm
Centrosome
Membrane
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
Cysteine-type Endopeptidase Activity
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
Cyclin Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Metal Ion Binding
Biological Process
DNA Recombination
Homologous Chromosome Pairing At Meiosis
Spermatogenesis
Meiotic DNA Double-strand Break Formation
Oogenesis
Regulation Of Homologous Chromosome Segregation
Negative Regulation Of Transcription By RNA Polymerase II
Ubiquitin-dependent Protein Catabolic Process
Cell Cycle
Muscle Organ Development
Protein Deubiquitination
Protein Phosphopantetheinylation
Circadian Regulation Of Gene Expression
Entrainment Of Circadian Clock By Photoperiod
Locomotor Rhythm
Positive Regulation Of Mitotic Cell Cycle
Circadian Behavior
Protein Stabilization
Pathways
TNFR1-induced proapoptotic signaling
Regulation of TNFR1 signaling
TNFR1-induced NFkappaB signaling pathway
Ub-specific processing proteases
Regulation of TP53 Degradation
Drugs
Diseases
GWAS
Refractive error (
32231278
)
Serum uric acid levels (
30993211
)
Urate levels (
31985003
31578528
23263486
)
Interacting Genes
78 interacting genes:
ABI2
ABI3
ADAMTS12
AQP1
ARHGEF9
ATP6V0D1
BCL6
BOLA2
BOLA2B
C1orf109
CARD9
CCDC120
CCDC57
CDC23
CFAP206
COX5B
DGCR6
DVL2
DYNLL1
DYNLL2
EAF2
EFHC1
EXOC8
FAM124A
FAM124B
FANCG
FANCL
FASLG
FHL3
FKBP6
GEM
GLRX3
GLYCTK
GOLGA2
GRAP2
GYS1
HEXIM2
HINFP
IQUB
KANK2
KIF9
KIFC3
KLC3
KLHL11
LMO2
LNX1
LONRF1
MAGEB4
MAGOHB
MAPK9
MID2
MRFAP1L1
MVP
MYO15B
NEK6
NFKBID
NGB
PICK1
POLR1C
PRKAB2
PRR34
RABGEF1
RAD51D
RHOBTB3
RUNX1T1
SDCBP
SMARCB1
STK25
TNS2
TRIM14
TRIM42
TTC19
USP2
USP20
ZGPAT
ZKSCAN3
ZNF417
ZNF688
163 interacting genes:
ABI2
ACTN1
ACTN2
ACTN3
APP
ASPG
ATN1
AURKA
BAP1
BCAR1
BCL2L2-PABPN1
BEGAIN
BEND5
BHLHB9
BICD2
BIRC7
BRCA1
CADPS
CALCOCO2
CARD9
CBLC
CCDC136
CCDC57
CCDC85B
CCDC88B
CCND1
CEP63
CEP70
CRACR2A
CRACR2B
CRY1
CTNNB1
DDI1
DEPDC5
DISC1
DTX3
DUSP21
DYDC1
EFHC2
EIF4ENIF1
ENPP1
ERBB2
EXOC5
EXOSC8
GEMIN4
GOLGA2
GOLGA6A
GOLGA6L9
GRB7
GRIPAP1
H2AC20
HOMER3
HOOK1
HOOK2
IHO1
IKBKG
IKZF3
IL1RL2
INTS11
JAKMIP1
JRK
KAZN
KIFC3
KRT15
KRT27
KRT31
KRT33B
KRT34
KRT35
KRT40
LHX3
LHX4
LMNA
LMNB2
LNX2
LONRF1
LRSAM1
LZTS2
MALT1
MAP3K2
MDM2
MID2
MNAT1
MORN5
MRPL28
MTUS2
MYC
NAB2
NDEL1
NEFL
NFKB2
NOTCH1
OIP5
OPTN
ORC3
ORC5
PALB2
PCGF6
PCNA
PEX5
PIBF1
PICK1
PIK3R3
PLA2G2A
PLEKHG4
PNMA1
POU2AF1
PRDM14
PRR5L
RABEP1
RAD18
RBCK1
RFX6
RNF125
RNF126
RNF144B
RNF166
RUNDC3A
S100A10
SH2B2
SNCA
SORBS3
SPAG8
SPDYE4
STAT5B
TAX1BP1
TEKT4
TFIP11
TGFBR1
TLE5
TNFAIP2
TRAF1
TRAF2
TRAF6
TRAIP
TRIM21
TRIM23
TRIM27
TRIM34
TRIM35
TRIM39
TRIM46
TRIM5
TRIM50
TRIM54
TRIM63
TRIM74
TRIM8
TRIM9
TRIP6
UBE2S
UBOX5
USHBP1
USP15
USP21
USP54
VCAM1
VPS28
VPS52
ZAP70
ZBED1
ZIM2
ZRANB1
Entrez ID
339834
9099
HPRD ID
14172
05287
Ensembl ID
ENSG00000173421
ENSG00000036672
Uniprot IDs
B4DZP6
Q8IYA8
O75604
PDB IDs
2HD5
2IBI
3NHE
3V6C
3V6E
5XU8
5XVE
6DGF
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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