ASF1A and ST13

Data Source:
HPRD (in vitro)

		ASF1A	ST13
Description		anti-silencing function 1A histone chaperone	ST13 Hsp70 interacting protein
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Protein-containing Complex	Cytoplasm Cytosol Protein-containing Complex Extracellular Exosome
	Molecular Function	Chromatin Binding Protein Binding Histone Binding	Protein Binding Protein Domain Specific Binding Hsp70 Protein Binding Protein-macromolecule Adaptor Activity Heat Shock Protein Binding DATP Binding Identical Protein Binding Protein-containing Complex Binding Protein Dimerization Activity Unfolded Protein Binding Chaperone Binding
	Biological Process	Osteoblast Differentiation DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Negative Regulation Of Chromatin Silencing Muscle Cell Differentiation	Protein Folding Response To Bacterium Chaperone Cofactor-dependent Protein Refolding Negative Regulation Of Protein Refolding Protein-containing Complex Assembly
Pathways		Formation of Senescence-Associated Heterochromatin Foci (SAHF)	Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS		Mean platelet volume ( 32888494) Multiple sclerosis ( 31604244) QT interval ( 19305408)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Feeling nervous ( 29500382) Refractive error ( 32231278)
Interacting Genes		35 interacting genes: ASF1B CDAN1 CHAF1A CHAF1B CHEK2 H3-3A H3-4 H3C3 H3C6 H4-16 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 HIRA HTATIP2 MCM2 NASP PAFAH1B2 PRR3 ST13 TAF1 TLK1 TLK2 VPS28 ZDHHC17	20 interacting genes: ALB APOE ASF1A CD101 CDC42 CTRC CXCR2 F2 HSP90AA1 HSPA1A HSPA1B HSPA4 HSPA8 NOS3 OLFM2 PSEN1 PTGER4 SMAD2 TTR VAV2
Entrez ID		25842	6767
HPRD ID		16459	08426
Ensembl ID		ENSG00000111875	ENSG00000100380
Uniprot IDs		Q9Y294	A0A140VKA6 B4E0U6 P50502 Q0IJ56
PDB IDs		1TEY 2I32 2IIJ 2IO5 3AAD 5C3I 6F0F 6F0G 6F0H	1UZS
Enriched GO Terms of Interacting Partners?
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