LCE5A and KRTAP5-4

Data Source:
BioGRID (two hybrid)

		LCE5A	KRTAP5-4
Description		late cornified envelope 5A	keratin associated protein 5-4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytosol Keratin Filament
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Keratinization	Keratinization
Pathways		Formation of the cornified envelope	Keratinization
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic march ( 26542096) Hair morphology ( 19896111) Inflammatory skin disease ( 25574825)
Interacting Genes		66 interacting genes: ADAM12 ALPP CHIC2 CHRD CREB5 CYP21A2 CYSRT1 FBLN1 HOXA1 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP12-4 KRTAP21-2 KRTAP3-1 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-2 KRTAP9-3 LCE1A LCE1B LCE1C LCE1E LCE1F LCE2B LCE2C LCE4A NBPF19 NECTIN2 NOTCH2NLA NTAQ1 NUTF2 PLAC8 PLSCR2 PLSCR3 PLSCR4 POU4F2 RGS17 RGS20 RNF4 SLC39A7 SMCP SPRED2 SPRY1 TRIM42 UBE2I VWC2L ZNF655	36 interacting genes: ADAMTSL4 BAG5 CATSPER1 CRCT1 CREB5 CRY2 CYSRT1 HOXA1 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP11-1 KRTAP5-2 KRTAP5-9 KRTAP9-2 KRTAP9-3 LCE1B LCE1C LCE1D LCE1E LCE1F LCE2C LCE3A LCE3B LCE3C LCE4A LCE5A MEOX2 NBPF19 NOTCH2NLA NUFIP2 PLEKHF2 POU4F2 RGS17 SMCP UBE2I
Entrez ID		254910	387267
HPRD ID		17265	12396
Ensembl ID		ENSG00000186207	ENSG00000241598
Uniprot IDs		Q5TCM9	A8MUN0 Q6L8H1
PDB IDs
Enriched GO Terms of Interacting Partners?
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