RICTOR and ANXA10

Data Source:
BioGRID (affinity chromatography technology)

		RICTOR	ANXA10
Description		RPTOR independent companion of MTOR complex 2	annexin A10
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol TORC2 Complex	Cytoplasm
	Molecular Function	Protein Binding Protein Kinase Binding Ribosome Binding Protein Serine/threonine Kinase Activator Activity	Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding
	Biological Process	Positive Regulation Of Endothelial Cell Proliferation Embryo Development Ending In Birth Or Egg Hatching Regulation Of Gene Expression Viral Process Peptidyl-serine Phosphorylation Positive Regulation Of Actin Filament Polymerization Actin Cytoskeleton Reorganization Positive Regulation Of TOR Signaling Activation Of Protein Kinase B Activity Regulation Of Actin Cytoskeleton Organization Regulation Of Peptidyl-serine Phosphorylation TORC2 Signaling Regulation Of GTPase Activity Regulation Of Inflammatory Response Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Protein Kinase B Signaling Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Establishment Of Cell Polarity
Pathways		PIP3 activates AKT signaling CD28 dependent PI3K/Akt signaling VEGFR2 mediated vascular permeability Constitutive Signaling by AKT1 E17K in Cancer Regulation of TP53 Degradation
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Immature fraction of reticulocytes ( 32888494) Obesity-related traits ( 23251661) Post bronchodilator FEV1 ( 26634245) Red blood cell count ( 32888494)	Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis) ( 29678681) Pursuit maintenance gain ( 29064472) Verbal declarative memory ( 25648963)
Interacting Genes		11 interacting genes: CHUK CUL1 EIF4EBP1 GSK3A GSK3B IKBKB ILK MTOR PLK1 SGK1 SIRT1	2 interacting genes: BLVRB EDC3
Entrez ID		253260	11199
HPRD ID		10682	09724
Ensembl ID		ENSG00000164327	ENSG00000109511
Uniprot IDs		Q6R327	Q9UJ72
PDB IDs		5ZCS
Enriched GO Terms of Interacting Partners?
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