PRPF6 and SRRM2

Data Source:
BioGRID (two hybrid)

		PRPF6	SRRM2
Description		pre-mRNA processing factor 6	serine/arginine repetitive matrix 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Membrane Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Cajal Body Nuclear Speck U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Transcription Coactivator Activity RNA Binding Protein Binding Ribonucleoprotein Complex Binding Androgen Receptor Binding	RNA Binding MRNA Binding Protein N-terminus Binding C2H2 Zinc Finger Domain Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Localization RNA Splicing Positive Regulation Of Transcription By RNA Polymerase II	MRNA Splicing, Via Spliceosome
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Body mass index ( 28552196) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Prostate cancer ( 23535732) Refractive error ( 32231278)	Height ( 31562340) Venous thromboembolism ( 32232851)
Interacting Genes		12 interacting genes: AR ARAF CD2BP2 ESR1 NR3C1 RAF1 SMARCA2 SRRM2 SUMO2 TIMM44 TXNL4B YWHAB	14 interacting genes: APP CLK1 CSNK2A1 PIN1 PNN PRPF6 SRPK2 SRRM1 SRSF4 SUMO2 TTC14 XRN1 YWHAB YWHAG
Entrez ID		24148	23524
HPRD ID		10729	06913
Ensembl ID		ENSG00000101161	ENSG00000167978
Uniprot IDs		O94906	A0A140VK53 Q9UQ35
PDB IDs		3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9	5MQF 5XJC 5YZG 5Z56 5Z57 6FF4 6FF7 6ICZ 6QDV 6ZYM 7A5P
Enriched GO Terms of Interacting Partners?
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