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OXER1 and ANAPC11
Data Source:
BioGRID
(two hybrid)
OXER1
ANAPC11
Description
oxoeicosanoid receptor 1
anaphase promoting complex subunit 11
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Membrane
Nucleus
Nucleoplasm
Anaphase-promoting Complex
Nucleolus
Cytosol
Cullin-RING Ubiquitin Ligase Complex
Molecular Function
G Protein-coupled Receptor Activity
Protein Binding
5-oxo-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding
5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding
5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ubiquitin-ubiquitin Ligase Activity
Ubiquitin Protein Ligase Activity
Cullin Family Protein Binding
Biological Process
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Mitotic Cell Cycle
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Anaphase-promoting Complex-dependent Catabolic Process
Positive Regulation Of Mitotic Metaphase/anaphase Transition
Cell Division
Protein K11-linked Ubiquitination
Regulation Of Mitotic Cell Cycle Phase Transition
Pathways
Eicosanoid ligand-binding receptors
G alpha (i) signalling events
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
CDK-mediated phosphorylation and removal of Cdc6
Transcriptional Regulation by VENTX
Aberrant regulation of mitotic exit in cancer due to RB1 defects
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Attention deficit hyperactivity disorder (
18821565
)
Breastfeeding duration (
25475840
)
Hyperactive-impulsive symptoms (
18821565
)
Interacting Genes
46 interacting genes:
ANAPC11
ARRB2
ASB13
ATG9A
CCNK
CRYBA2
EFCAB3
ESRP1
FOXH1
HNF1B
HNRNPH1
INTS11
JMJD7
KRTAP12-3
KRTAP19-5
KRTAP4-2
KRTAP5-6
KRTAP6-3
LASP1
MED25
NCS1
NEK8
NOC4L
OTX1
PLSCR4
PRKAB2
PROP1
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PRR35
RAMAC
RBFOX2
RECK
RNF208
RNF38
RNF44
TFG
TLE5
TP53BP1
VGLL3
ZBTB32
ZC3H10
ZIC1
55 interacting genes:
ANAPC10
ANAPC2
ANAPC4
BANP
BEND2
CAPN11
CCNB1
CDC16
CDC20
CREB5
CRYBA2
CUL5
CYSRT1
DTX2
EFEMP1
EFEMP2
FBXO5
FRS3
FZR1
GPANK1
HSD3B7
IQUB
KRTAP11-1
KRTAP13-2
KRTAP19-2
KRTAP3-1
KRTAP3-3
KRTAP6-1
KRTAP6-2
MAK
MGAT5B
MLKL
NKD2
OXER1
P4HA3
PRKAA2
PRKAB2
PTTG1
RBPMS
RNF111
TCEANC
TEX37
TLE5
TRIM65
UBC
UBE2C
UBE2D1
UBE2D2
UBE2D3
UBE2K
UBE2L1
UBE2S
UBE2U
WWOX
ZAP70
Entrez ID
165140
51529
HPRD ID
17812
12452
Ensembl ID
ENSG00000162881
ENSG00000141552
Uniprot IDs
Q8TDS5
A0A024R8S1
Q9NYG5
PDB IDs
2MT5
4R2Y
4UI9
5A31
5G04
5G05
5JG6
5KHR
5KHU
5L9T
5L9U
5LCW
6Q6G
6Q6H
6TLJ
6TM5
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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