GNA13 and AKAP3

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, in vitro, two hybrid)

		GNA13	AKAP3
Description		G protein subunit alpha 13	A-kinase anchoring protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Heterotrimeric G-protein Complex Plasma Membrane Focal Adhesion Membrane Brush Border Membrane Melanosome Extracellular Exosome	Acrosomal Vesicle Nucleus Cytoplasm Sperm Fibrous Sheath Sperm Midpiece Sperm Principal Piece
	Molecular Function	G Protein-coupled Receptor Binding GTPase Activity Protein Binding GTP Binding G-protein Beta/gamma-subunit Complex Binding D5 Dopamine Receptor Binding Metal Ion Binding	Protein Binding Protein Kinase A Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Rho Protein Signal Transduction Platelet Activation Activation Of Phospholipase D Activity Positive Regulation Of Apoptotic Process Regulation Of Small GTPase Mediated Signal Transduction	Blastocyst Hatching Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Single Fertilization Acrosome Reaction Protein Localization
Pathways		NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events Thromboxane signalling through TP receptor Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs)
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Periventricular white matter hyperintensities ( 32517579) White matter microstructure (global fractional anisotropy) ( 24736177)	Gut microbiota (bacterial taxa) ( 27723756)
Interacting Genes		31 interacting genes: AIP AKAP3 ARHGEF1 ARHGEF11 ARHGEF12 CDH1 CDH2 CTNNB1 CXCR4 DRD5 EDNRB F2R GNA12 GPR17 MCF2 MTNR1A PPP5C PRKACA PRKCB PRKCD PRKCE PTK2B RDX RGS16 RIC8A S1PR2 S1PR3 S1PR4 TBXA2R TGFBR1 TSHR	8 interacting genes: AKAP4 BRAP GNA13 PRKAR2A ROPN1 ROPN1B ROPN1L SPA17
Entrez ID		10672	10566
HPRD ID		05100	05256
Ensembl ID		ENSG00000120063	ENSG00000111254
Uniprot IDs		A0A024R8M0 Q14344	O75969 V9HWD4
PDB IDs
Enriched GO Terms of Interacting Partners?
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