PLEKHG1

Description pleckstrin homology and RhoGEF domain containing G1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653)
  • Alcohol and nicotine co-dependence ( 22488850)
  • Alzheimer's disease (cognitive decline) ( 23535033)
  • Blood pressure ( 23972371)
  • Blood pressure traits (multi-trait analysis) ( 28498854)
  • Cadmium levels ( 26025379)
  • Coronary artery disease ( 29212778)
  • Diastolic blood pressure ( 27841878 28739976 27618452 28498854)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Hematocrit ( 32888494)
  • Malaria ( 31844061)
  • Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Medication use (calcium channel blockers) ( 31015401)
  • Medication use (diuretics) ( 31015401)
  • Obesity-related traits ( 23251661)
  • Panic disorder ( 19165232)
  • Periventricular white matter hyperintensities ( 32517579)
  • Red cell distribution width ( 32888494)
  • Systolic blood pressure ( 27841878 28739976 27618452 28498854 30578418)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Systolic blood pressure in sickle cell anemia ( 24058526)
  • Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • White matter hyperintensities ( 32358547)
  • White matter hyperintensity volume ( 30659137)
Novel Interacting Genes 1 novel interacting genes: ARID1B
Interacting Genes 2 interacting genes: CDC42 RAC1
Entrez ID 57480
HPRD ID 18850
Ensembl ID ENSG00000120278
Uniprot IDs Q5JYA6 Q9ULL1
PDB IDs
Enriched GO Terms of Interacting Partners?
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