KRT1 and FANCC

Number of citations of the paper that reports this interaction (PubMedID 14499622)
15

Data Source:
BioGRID (two hybrid)

		KRT1	FANCC
Description		keratin 1	FA complementation group C
Image			No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Extracellular Region Extracellular Space Nucleus Cytosol Cytoskeleton Membrane Keratin Filament Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle Ficolin-1-rich Granule Lumen	Nucleus Nucleoplasm Cytoplasm Cytosol Fanconi Anaemia Nuclear Complex
	Molecular Function	Protein Binding Carbohydrate Binding Structural Constituent Of Skin Epidermis Signaling Receptor Activity Protein Heterodimerization Activity	Protein Binding
	Biological Process	Complement Activation, Lectin Pathway Retina Homeostasis Response To Oxidative Stress Peptide Cross-linking Fibrinolysis Regulation Of Angiogenesis Negative Regulation Of Inflammatory Response Protein Heterotetramerization Establishment Of Skin Barrier	Myeloid Cell Homeostasis DNA Repair Nucleotide-excision Repair Germ Cell Development Removal Of Superoxide Radicals Cellular Response To Oxidative Stress Interstrand Cross-link Repair Brain Morphogenesis Protein-containing Complex Assembly Neuronal Stem Cell Population Maintenance
Pathways		Neutrophil degranulation Keratinization Formation of the cornified envelope	Fanconi Anemia Pathway TP53 Regulates Transcription of DNA Repair Genes
Drugs		Zinc Copper Zinc acetate
Diseases
GWAS			Birth weight ( 31043758) Hematocrit ( 32888494) Offspring birth weight ( 31043758) Polycystic ovary syndrome ( 26284813)
Interacting Genes		54 interacting genes: - AMOTL2 CALB2 CSTA DSP EVPL F12 FANCA FANCC FFAR2 GOLGA2 GOLGA6L9 HAUS1 HMG20A HOOK2 IVL KNG1 KRT13 KRT14 KRT15 KRT16 KRT19 KRT24 KRT25 KRT26 KRT27 KRT28 KRT31 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT5 KRT6A LINC00839 LORICRIN MBL2 NINL NUP62 OGT PDE4DIP PI3 PRKCE RINT1 SGTB TFIP11 TLCD4 TRIM54 U2AF1 UBE3A YWHAQ	54 interacting genes: APC AZIN1 BMPR1A BUB1 CAPN10 CCNA2 CCND1 CDK1 CTBP1 DLC1 DNAJB1 EGFR FANCA FANCD2 FANCE FANCF FANCG FBXW7 GSTP1 HSP90AA1 HSP90B1 HSPA1A HSPA4 HSPA8 IK KRAS KRT1 MEOX2 MLH3 MT-ATP6 MUTYH NRAS PDGFRL PIK3CA PMS2 POR PRDX3 PRPF31 PTPN12 PTPRJ RB1 RPL18 RPS3A SMAD4 SPTA1 SPTAN1 SRC STAT1 STMN1 STMN2 TCERG1 TGFBR2 USP14 ZBTB32
Entrez ID		3848	2176
HPRD ID		00763	01967
Ensembl ID		ENSG00000167768	ENSG00000158169
Uniprot IDs		P04264	A0A024R9N2 A0A087WW44 B4E3W2 Q00597
PDB IDs		4ZRY 6E2J 6UUI
Enriched GO Terms of Interacting Partners?
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