AREL1

Description		apoptosis resistant E3 ubiquitin protein ligase 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Protein Ubiquitination Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Inflammatory Response
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		General factor of neuroticism ( 30867560) Glaucoma (primary open-angle) ( 33627673) Mood instability ( 29187730)
Interacting Genes		12 interacting genes: CRKL DIABLO HTRA2 NPC2 PIAS4 RGS6 SEPTIN4 UBC UBE2D1 UBE2D2 UBE2D3 UBE2L3
Entrez ID		9870
HPRD ID		13794
Ensembl ID		ENSG00000119682
Uniprot IDs		O15033
PDB IDs		6JX5 6LOH
Enriched GO Terms of Interacting Partners?
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