IST1

Description		IST1 factor associated with ESCRT-III
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GO Annotations	Cellular Component	Chromatin Extracellular Region Nuclear Envelope Endoplasmic Reticulum-Golgi Intermediate Compartment Centrosome Cytosol Midbody Azurophil Granule Lumen Intracellular Membrane-bounded Organelle Extracellular Exosome Flemming Body
	Molecular Function	Protein Binding Protein Domain Specific Binding Protein-containing Complex Binding Cadherin Binding MIT Domain Binding
	Biological Process	Protein Localization Abscission Protein Transport Viral Release From Host Cell Multivesicular Body Assembly Establishment Of Protein Localization Positive Regulation Of Proteolysis Viral Capsid Secondary Envelopment Positive Regulation Of Collateral Sprouting Cell Division Cytoskeleton-dependent Cytokinesis ESCRT III Complex Disassembly
Pathways		Neutrophil degranulation Sealing of the nuclear envelope (NE) by ESCRT-III
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Blood protein levels ( 28240269) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Intelligence (MTAG) ( 29326435) Response to anti-TNF therapy in rheumatoid arthritis ( 26776603) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		11 interacting genes: APEH ATXN1 BAG4 CALB2 CAPN7 CHMP1A OGT SPAST TOX3 UBQLN1 UBQLN2
Entrez ID		9798
HPRD ID		13784
Ensembl ID		ENSG00000182149
Uniprot IDs		B4DXC9 P53990
PDB IDs		3FRR 3FRS 3JC1 4U7E 4U7I 4U7Y 4WZX 6E8G 6TZ4 6TZ5 6TZA
Enriched GO Terms of Interacting Partners?
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