DOCK4

Description		dedicator of cytokinesis 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleolus Golgi Apparatus Cytosol Plasma Membrane Membrane Stereocilium Stereocilium Bundle
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding SH3 Domain Binding PDZ Domain Binding Receptor Tyrosine Kinase Binding Small GTPase Binding
	Biological Process	Small GTPase Mediated Signal Transduction Regulation Of Catalytic Activity Cell Chemotaxis Negative Regulation Of Vascular Associated Smooth Muscle Contraction Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration
Pathways		RAC1 GTPase cycle RAC2 GTPase cycle RHOG GTPase cycle Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Body mass index (change over time) ( 25378290) C-reactive protein and white blood cell count ( 22788528) Migraine ( 27322543) Refractive astigmatism ( 30306274) Refractive error ( 32231278) Response to fenofibrate ( 22890011) Total intracranial volume ( 31530798)
Interacting Genes		4 interacting genes: ELMO2 FASLG GRB2 RNF115
Entrez ID		9732
HPRD ID		07407
Ensembl ID		ENSG00000128512
Uniprot IDs		Q8N1I0
PDB IDs
Enriched GO Terms of Interacting Partners?
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