ARHGEF10

Description		Rho guanine nucleotide exchange factor 10
Image		No pdb structure
GO Annotations	Cellular Component	Centrosome Cytosol
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Kinesin Binding
	Biological Process	Myelination In Peripheral Nervous System Actin Cytoskeleton Organization Regulation Of Rho Protein Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Centrosome Duplication Positive Regulation Of Stress Fiber Assembly Mitotic Spindle Assembly Activation Of GTPase Activity
Pathways		NRAGE signals death through JNK G alpha (12/13) signalling events RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Cleft lip with or without cleft palate x maternal periconceptional alcohol use interaction (parent of origin effect) ( 31372216) Delta-6 desaturase activity response to n3-polyunsaturated fat supplement ( 29246731) End-stage renal disease ( 29885931) HOMA-B (corrected for HOMA-IR) ( 30369944) Multiple sclerosis ( 23412934) Optic disc size ( 31809533) Toenail selenium levels ( 25343990)
Interacting Genes		5 interacting genes: CDC42 FHL3 PINX1 RAC1 RHOA
Entrez ID		9639
HPRD ID		09735
Ensembl ID		ENSG00000104728
Uniprot IDs		O15013
PDB IDs
Enriched GO Terms of Interacting Partners?
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