TNFSF12

Description		TNF superfamily member 12
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Signaling Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding Protein Binding Receptor Ligand Activity
	Biological Process	Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Apoptotic Process Immune Response Signal Transduction Cell Differentiation Endothelial Cell Migration Positive Regulation Of Protein Catabolic Process Positive Regulation Of Angiogenesis Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		TNFR2 non-canonical NF-kB pathway TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
Drugs
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30643258) Apolipoprotein A1 levels ( 32203549) Atrial fibrillation ( 30061737 29892015) Blood protein levels ( 29875488) Brain morphology (MOSTest) ( 32665545) Chin dimples ( 27182965) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Emotional recognition ( 31596458) HDL cholesterol levels ( 32203549) Myopia ( 27182965) Plateletcrit ( 32888494) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Triglyceride levels ( 32203549) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		6 interacting genes: AGGF1 DDIT3 LMNA SGTA TNFRSF12A TNFRSF25
Entrez ID		8742
HPRD ID		04074
Ensembl ID		ENSG00000239697
Uniprot IDs		O43508 Q4ACW9
PDB IDs		4HT1
Enriched GO Terms of Interacting Partners?
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