ADAM19

Description		ADAM metallopeptidase domain 19
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Golgi Apparatus Plasma Membrane Integral Component Of Membrane Collagen-containing Extracellular Matrix
	Molecular Function	Metalloendopeptidase Activity Protein Binding SH3 Domain Binding Metal Ion Binding Metalloendopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process
	Biological Process	Placenta Development Membrane Protein Ectodomain Proteolysis Positive Regulation Of Gene Expression Protein Processing Amyloid Precursor Protein Catabolic Process Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin
Pathways		Invadopodia formation
Drugs
Diseases
GWAS		Asthma ( 31959851) Blood protein levels ( 30072576) Body mass index ( 28552196) Chronic obstructive pulmonary disease ( 28166215 30804561 33909500) Eosinophil percentage of white cells ( 32888494) FEV1 ( 30804560) Inflammatory skin disease ( 25574825) Lung function (FEV1/FVC) ( 28166213 30804560) Medication use (adrenergics, inhalants) ( 31015401) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Peak expiratory flow ( 30804560) Pulmonary function ( 20010835) Pulmonary function (smoking interaction) ( 23284291) T-Cell Immunoglobulin and Mucin domain 1 levels ( 32460577) Triglyceride levels ( 31647587)
Interacting Genes		7 interacting genes: A2M ABI2 COPB1 FURIN NRG1 SH3GL2 TNFSF11
Entrez ID		8728
HPRD ID		04704
Ensembl ID		ENSG00000135074
Uniprot IDs		Q8TBU7 Q9H013
PDB IDs
Enriched GO Terms of Interacting Partners?
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