SUPT3H

Description		SPT3 homolog, SAGA and STAGA complex component
Image		No pdb structure
GO Annotations	Cellular Component	SAGA Complex Nucleus Nucleoplasm Transcription Factor TFTC Complex
	Molecular Function	Transcription Coactivator Activity Protein Heterodimerization Activity
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Histone Deubiquitination Histone H3 Acetylation Positive Regulation Of Transcription, DNA-templated
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS		ADAMTS13 activity ( 25934476) Attention deficit hyperactivity disorder ( 18839057) Chin dimples ( 27182965) Estimated glomerular filtration rate ( 31152163) facial morphology traits (multivariate analysis) ( 27193062) Glaucoma ( 31959993) Heel bone mineral density ( 30598549 28869591) Height ( 28552196 25282103 25429064 19893584 23563607 31562340 18391951) Hip circumference adjusted for BMI ( 34021172) Hip minimal joint space width ( 27701424) Intraocular pressure ( 31959993 30054594) Large artery stroke ( 24262325) Lumbar spine bone mineral density ( 22504420) Lymphocyte counts ( 32888494) Male-pattern baldness ( 27182965) Monobrow ( 27182965) Nose morphology ( 29921221) Nose size ( 27182965) Obesity-related traits ( 23251661) Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 27021288) Ossification of the posterior longitudinal ligament of the spine ( 25064007) Osteoarthritis ( 22763110) Osteoarthritis of the hand ( 28855172) Osteoarthritis of the hip or knee ( 30664745) Post bronchodilator FEV1/FVC ratio ( 26634245) Serum alkaline phosphatase levels ( 33547301) Stroke (ischemic) ( 22941190) Triglyceride levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder ( 33824429) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		5 interacting genes: DDB1 H3-4 MYC PYGO2 TCF3
Entrez ID		8464
HPRD ID		04254
Ensembl ID		ENSG00000196284
Uniprot IDs		A0A024RD67 B4E1H0 O75486
PDB IDs
Enriched GO Terms of Interacting Partners?
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