DIAPH3

Description		diaphanous related formin 3
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol
	Molecular Function	Actin Binding Small GTPase Binding Cadherin Binding
	Biological Process	Cytoskeleton Organization Actin Cytoskeleton Organization Actin Filament Polymerization
Pathways		RHO GTPases Activate Formins RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOQ GTPase cycle RHOG GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle RHOF GTPase cycle
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 27089180 34211149) Body mass index ( 28892062) Breast milk fatty acid composition (infant genotype effect) ( 29514873) Breast milk fatty acid composition (maternal genotype effect) ( 29514873) Chronotype ( 30696823) General risk tolerance (MTAG) ( 30643258) Gut microbiota (functional units) ( 27694959) HOMA-B (corrected for HOMA-IR) ( 30369944) Metabolite levels ( 23823483) Neonatal total 25-hydroxyvitamin D levels (maternal genetic effect) ( 32047095) Number of sexual partners ( 30643258) Smoking initiation ( 33082346) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		6 interacting genes: CDC42 NCKIPSD PDCD6 RAC1 RHOA SMAD9
Entrez ID		81624
HPRD ID		10884
Ensembl ID		ENSG00000139734
Uniprot IDs		B4DPV3 Q9NSV4
PDB IDs		5UWP 6X2Y
Enriched GO Terms of Interacting Partners?
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