UFD1

Description		ubiquitin recognition factor in ER associated degradation 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol VCP-NPL4-UFD1 AAA ATPase Complex UFD1-NPL4 Complex
	Molecular Function	Thiol-dependent Deubiquitinase Signaling Receptor Binding Protein Binding Polyubiquitin Modification-dependent Protein Binding K48-linked Polyubiquitin Modification-dependent Protein Binding Protein-containing Complex Binding ATPase Binding
	Biological Process	Skeletal System Development Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent ERAD Pathway Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Type I Interferon Production Negative Regulation Of RIG-I Signaling Pathway ER-associated Misfolded Protein Catabolic Process
Pathways		Translesion Synthesis by POLH Ub-specific processing proteases
Drugs
Diseases
GWAS
Interacting Genes		23 interacting genes: A2M AMFR ANAPC2 CHMP2A F13A1 GZMK HSPB1 IGHM LRRK2 MAP3K1 MASP1 NGFR NPLOC4 NUB1 PIK3CA PPHLN1 SNX1 TAF1C TIAM2 TP53 UBC UBXN6 VCP
Entrez ID		7353
HPRD ID		06778
Ensembl ID		ENSG00000070010
Uniprot IDs		Q541A5 Q92890
PDB IDs		2YUJ 5B6C 5C1B
Enriched GO Terms of Interacting Partners?
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